The effect of platelet-rich plasma (PRP) on fracture healing time and clinical outcome in patients with intertrochanteric fracture: A randomized double-blind placebo-controlled clinical trial
Phase 3
Recruiting
- Conditions
- Fracture in intertrochanteric region that requires fixation with cephalomedullary nailHip fractureIntertrochanteric fractureCephalomedullary nailPFNAPlatelet rich plasmaPRP
- Registration Number
- TCTR20210515001
- Lead Sponsor
- Ratchasapisek Sompoch
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 86
Inclusion Criteria
1. Patients with intertrochanteric fracture that were admitted in King Chulalongkorn Memorial Hospital
2. Patients with age > 60
3. No associated fracture
4. Patients who were household or community ambulator prior to injury
Exclusion Criteria
1. Patients who deny surgery or unable to surgery due to severe comorbidity
2. Recent use of NSAIDs, aspirin or any drugs that will interact with platelets function
3. Patients with hematologic disease
4. Patients with history of hip fracture
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time of fracture healing 2, 6, 12, 24, 48 weeks Bridging callus from plain film
- Secondary Outcome Measures
Name Time Method Harris Hip score 2, 6, 12, 24, 48 weeks Questionaire,de Morton Mobility Index (DEMMI) 2, 6, 12, 24, 48 weeks Questionaire,Barthel index score 2, 6, 12, 24, 48 weeks Questionaire,Functional Reach Test 2, 6, 12, 24, 48 weeks Questionaire,Five Times Sit to Stand 2, 6,12, 24, 48 weeks Questionaire,Time up and go test 2, 6,12, 24, 48 weeks Questionaire,pain visual analog scalre 2, 6,12, 24, 48 weeks Questionaire