Fractional carbondioxide laser with and without platelet rich plasma therapy in treatment of acne scars

Completed

• Conditions: Scar conditions and fibrosis of skin,

• Registration Number: CTRI/2023/09/057562
• Lead Sponsor: Dr Sanaga Mrudula

Brief Summary

This study is a randomized,double blind,parallel group,active control interventional study comparing the efficacy and safety profile of fractional co2 laser with and without platelet rich plasma therapy in the treatment of acne scars.This study will be conducted over a period of 1 year 3 months at a single centre in India. The primary outcome measures will be improvement in acne scars 1 month after each session.Secondary outcomes will be incidence of side effects which are assessed 1 week after each session.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-30
• Study Completion: 2025-03-31
• Last Update Posted: 2025-05-17

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• 1. Patients who are willing to take part in the research.
• 2)Fitzpatrick’s skin type III-V patients aged 18-40 years with moderate to severe facial acne scars (i.e. Grade 3 and 4 according to Goodman and Baron qualitative grading of acne scars.

Exclusion Criteria

• 1. Women who are pregnant or breastfeeding.
• 2. Patients with local infection at the site of procedure (HSV, bacterial, etc,.) 3) Patients with a history of photosensitive disorders.
• 4. Patients who have bleeding diathesis.
• 5. Patients who are on anticoagulant therapy.
• 6. Patients who are immunocompromised or taking any immunosuppressive drugs 7) Patients who are suffering from body dysmorphic syndrome or acne excoriee and those who have unrealistic expectations.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in acne scar apperance	1 month after each session

Secondary Outcome Measures

Name	Time	Method
incidence of Side effects	1 week after each session

Trial Locations

Locations (1)

Katuri Medical College and Hospital; 🇮🇳 Guntur, ANDHRA PRADESH, India

Katuri Medical College and Hospital

🇮🇳Guntur, ANDHRA PRADESH, India

Dr Sanaga Mrudula

Principal investigator

8125768669

mrudulasng1997@gmail.com