Reversal of neuromuscular blockade in laparoscopic cholecystectomy: Effect on postoperative gastrointestinal motility

Not Applicable

Completed

• Conditions: Diseases of the digestive system

• Registration Number: KCT0003856
• Lead Sponsor: The Catholic University of Korea, Uijeongbu St. Mary’s Hospital

Brief Summary

Administration of sugammadex reduces the time to postoperative first flatus in a dose-dependent manner compared to the conventional anticholinesterase, pyridostigmine, and glycopyrrolate. These observations suggested that sugammadex shows a positive effect in terms of recovery of postoperative gastrointestinal motility.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-04-15
• Last Update Posted: 28 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 99

Inclusion Criteria

1. patients who receive laparoscopic cholecystectomy under general anesthesia by endotracheal intubation
2. 19~48 years old female patients

Exclusion Criteria

1) patient < 19 years old , patient > 48 years old
2) American Society of Anesthesiology class > 2
3) present gastrointestinal disease
4) Laxative use
5) hypercalcemia
6) History of gastrointestinal surgery
7) Abnormal levels of serum electrolyte
8) Abnormal levels of thyroid hormones
9) DM patient
10) Allergy about medicine which is used in study
11) patient who does not fast more than 8 hours
12) patient who has been taking oral contraceptive

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
time to postoperative first flatus;time to postoperative first feces

Secondary Outcome Measures

Name	Time	Method
total amount of pain medicine in postoperative care unit and ward after surgery;total amount of antiemetic drug in postoperative care unit and ward after surgery