Inflammatory mediators in nasal discharge of chronic rhinosinusitis patients treated with erythromycin. - ECP

• Conditions: Effect of erythromycin therapy on the inflammatory mediators in nasal discharge of chronic rhinosinusitis patients.; MedDRA version: 9.1Level: LLTClassification code 10009137Term: Chronic sinusitis

• Registration Number: EUCTR2008-005828-84-DE
• Lead Sponsor: ENT Hospital, Johannes-Gutenberg University, Mainz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-01-28
• Last Update Posted: 15 July 2013

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

- Patients with chronic rhinosinusitis who underwent a sinus operation in the last month prior to study registration
- Age over 18 years
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- Pregnancy - Women of reproductive age not using adequate contraception. The following are considered effective means of contraception: surgical sterilization or use of oral contraceptives, barrier contraception with either a condom or diaphragm in conjunction with spermicidal gel, an IUD, or contraceptive hormone implant or patch - Significant renal or hepatic disorders - Cardiac arrhythmia - Cystic fibrosis - Primary ciliary dyskinesia - Immunodeficiency - Macrolide intolerance or allergy - Concomitant medication with drugs known to interact with macrolides

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified