Effects of Diet Control and Resistance Exercise Training on Obesity Adults With Knee Osteoarthritis in Pain Relief, Body Composition, Lower Limb Function and Quality of Life
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Osteoarthritis, Knee
- Sponsor
- Chang Gung Memorial Hospital
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- KOOS
- Last Updated
- 4 years ago
Overview
Brief Summary
The purpose of this study was to investigate the effects of obesity on knee degenerative arthritis on body composition after dietary control and elastic resistance exercise; and whether persistent exercise habits and dietary control can relieve pain and strengthen muscle strength. Improve the quality of life and the decline of other risk factors.
Detailed Description
Due to dietary westernization and overweight, the number of knee joint degeneration is increasing year by year. Degeneration of knee arthritis can lead to pain and not exercise, and thus other chronic diseases. When the weight loss exceeds 5.1%, the function of the knee joint can be significantly improved and low heat weight loss (1200 kcal / day) and very low heat weight loss (less than 800 kcal / day) both weight loss The results are equally good .Many studies have shown that early and mid-interventional resistance exercise can improve muscle weakness, pain and stiffness in patients with degenerative knee arthritis, and elastic resistance exercise can effectively improve lower limb function and increase physical activity in patients with knee arthritis However, there has been no research on the effects of diet control and resistance exercise training on pain relief, body composition, lower limb function and quality of life in obese knee degenerative arthritis. The purpose of this study was to explore the degenerative knee degeneration. The effect of arthritis on the composition of the body after a balanced diet calorie control and home-based low-intensity elastic resistance movement; and whether persistent exercise habits and diet control can relieve pain, strengthen muscle strength, improve quality of life and other risks The effect of factor decline. Expected to combine the diet control and home group exercise to improve the quality of life of patients with degenerative knee arthritis.
Investigators
yenyen0411
Dietitian，Investigator
Chang Gung Memorial Hospital
Eligibility Criteria
Inclusion Criteria
- •Cases of knee joint degeneration diagnosed by orthopedics, rheumatology and immunology physicians.
- •X-ray interpretation (kellgren \& Lawrence grade) grades 1 to 3 or mild to moderate patients.
- •Willing to sign written consent form.
- •Pain Index (VAS) ≧ 4/
- •Men and women over the age of
- •Body mass index (BMI) ≧ 27 kg/m\^2.
Exclusion Criteria
- •Unable to act on your own.
- •X-ray interpretation (kellgren \& Lawrence level) is greater than level 3 or is a serious level.
- •Patients who have undergone knee arthroplasty on one or both feet.
- •Patients with terminal liver and kidney disease.
- •Those who are unable to perform physical function measurement after severe diagnosis of heart and lung disease after diagnosis by the physician.
- •High blood pressure with poor control (systolic blood pressure greater than or equal to 180 mmHg at the time of return).
- •Pregnant women or breastfeeding women.
- •Those who have coronary stents, cardiac rhythms, or other metallic substances in the body are not recommended for total body composition analysis.
- •Those with severe hip, knee, and lower back pain who are unable to perform exercise, other neuromuscular, skeletal joints, or rheumatic diseases may be exacerbated by exercise. Or those who have musculoskeletal injuries in the past six months (such as bruises, fractures, etc.).
- •Unable to cooperate with the test or halfway through the test.
Outcomes
Primary Outcomes
KOOS
Time Frame: Baseline and after 3 months
KOOS is based on WOMAC and covers a wider range. The score of each topic is 0-4 points. The higher the score after the conversion formula, the better the knee joint function. This study assessed changes in KOOS scores, whether it was higher than baseline after 12 weeks.
WOMAC
Time Frame: Baseline and after 3 months
WOMAC is used to measure the patient's home knee function. Each question is scored using a five-point scale. The higher the score, the worse the knee function. This study assessed the amount of change in WOMAC scores, whether it was lower than baseline after 12 weeks.
Body fat percentage
Time Frame: Baseline and after 3 months
Assess the amount of body fat (%) change, whether it can be less than baseline after 12 weeks
Body Mass Index
Time Frame: Baseline and after 3 months
Assess the amount of Body Mass Index(kg/m\^2) change, whether it can be less than baseline after 12 weeks
waistline
Time Frame: Baseline and after 3 months
Waist circumference change from baseline to 12 weeks (cm)
Secondary Outcomes
- hand grip force measurement(Baseline and 3 months)
- Low-density cholesterol(Baseline and 3 months)
- triglyceride(Baseline and 3 months)
- 30 chair stand test(Baseline and 3 months)
- total cholesterol(Baseline and 3 months)
- 2.44m time up to go(Baseline and 3 months)