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Clinical Trials/NCT05274074
NCT05274074
Completed
Not Applicable

Improving Care Partner Outcomes Through Positive Connections

University of Rochester1 site in 1 country58 target enrollmentJuly 28, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Social Connectedness
Sponsor
University of Rochester
Enrollment
58
Locations
1
Primary Endpoint
Patient Reported Outcome Measurement Information System (PROMIS )Positive Affect
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study examines a behavioral intervention to improve social connection and reduce loneliness for caregivers of a loved one with Dementia with Lewy Bodies (DLB).

Detailed Description

The objective of the Social-LEAF study is to examine psychological mechanisms whereby Social LEAF delivered in a group and via video call reduces loneliness and improves positive emotions for older caregivers of loved ones with DLB. This is an 18-month Stage 2 study examining Social LEAF, which is strengths-based and teaches positive coping skills focused on improving social relationships and is delivered remotely in a group format. These two adaptations to the original LEAF intervention are included to provide a more potent means of improving social connection. A pilot phase with up to 20 caregivers (Aim 1) will address these adaptations regarding feasibility, acceptability, and signal for reducing loneliness, with refinements as needed. A second phase (Aims 2 and 3) will involve a randomized trial comparing Social LEAF to control (30 caregivers in each arm) on loneliness (primary outcome), positive affect (mechanism), and social engagement (mechanism). Data will also be collected on acceptability and perceived benefits using mixed methods. Aim 1 is to refine the LEAF intervention to target social relationships and loneliness. Aim 2 is to examine feasibility and acceptability of Social LEAF for DLB caregivers. Aim 3 is to examine efficacy of Social LEAF in reducing loneliness, increasing positive affect, and increasing social engagement.

Registry
clinicaltrials.gov
Start Date
July 28, 2022
End Date
July 23, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Benzi Kluger, MD

Professor

University of Rochester

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not a primary care partner of a person with DLB. Is a primary care partner of someone who has not been clinically diagnosed with DLB. Cannot speak English or provide clear and concise consent to the project.
  • Has not started LEAF procedures at the beginning and has taken part in Aim 1 of the study.
  • Has started/taken part in the LEAF procedures at the beginning and also has taken part in Aim 1 of the study.

Outcomes

Primary Outcomes

Patient Reported Outcome Measurement Information System (PROMIS )Positive Affect

Time Frame: Week 6

Change in the Patient Reported Outcomes Measurement Information System (PROMIS)- Positive Affect from Baseline to Week 6. This is a 15-item scale measuring momentary positive affective experiences over the past 7 days. It is a five-point Likert-type scale (i.e.,"not at all, a little bit, somewhat, quite a bit, very much") resulting in 15-75 scale. Scores are summed to create a raw score. Individual items are positively skewed with 5 options from "Not at all" to "Very much." Higher scores indicate better positive affect and are a better outcome.

Secondary Outcomes

  • Berkman-Syme Social Network Index(Week 6)
  • Patient Reported Outcome Measurement Information System (PROMIS) Social Isolation(Week 6)
  • Patient Reported Outcome Measurement Information System (PROMIS) Satisfaction Role Activities(Week 6)
  • Positive Aspects of Caregiving Scale(Week 6)
  • University of California Los Angeles (UCLA) Loneliness Scale(Week 6)

Study Sites (1)

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