NCT01696786
Completed
Not Applicable
Oocyte Cryopreservation
ConditionsFertility Preservation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fertility Preservation
- Sponsor
- Weill Medical College of Cornell University
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- Pregnancy rate following thawing/warming of oocytes
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The specific aim of this study is to further develop methods of oocyte cryopreservation and evaluate their impact on reproductive outcomes.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Any consenting female who wishes to freeze unfertilized oocytes and are:
- •at risk for ovarian hyperstimulation syndrome (enlarged ovaries with abdominal fluid accumulation) and postponement of pregnancy has been recommended.
- •a cancer patient anticipating treatment and have been cleared by the oncologists for ovarian stimulation.
- •a female who seeks to preserve her future fertility and does not wish to use donor or partner sperm to fertilize her eggs.
- •a donor egg recipient who elects to have some of the eggs obtained fertilized with husband/partner sperm and the rest cryopreserved for future use.
- •a patient for whom the partner's sperm retrieval or production has failed and donor sperm is not an option.
- •a patient who, for religious or ethical reasons, wants to limit the number of fresh oocytes exposed to sperm (fertilization) and do not want to either discard or donate the excess oocytes.
- •has been clinically and psychologically approved for ovarian stimulation
- •age between 12 and 42 years, inclusive, at time of informed consent.
- •willing and able to comply with the protocol.
Exclusion Criteria
- •Age \> 42 Subjects who do not meet the inclusion criteria will be ineligible for participation in this study.
Outcomes
Primary Outcomes
Pregnancy rate following thawing/warming of oocytes
Time Frame: 1 year
Pregnancy rate following thawing/warming of oocytes
Implantation rate per embryo transferred
Time Frame: 1 year
Implantation rate per embryo transferred
Survival rate of cryopreserved oocytes with each cryopreservation method
Time Frame: 1 year
Survival rate of cryopreserved oocytes with each cryopreservation method
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Investigational Oocyte Cryopreservation for Medical and Non Medical IndicationsInfertility, FemaleDeferred ChildbearingNCT04616417University of Illinois at Chicago29
Terminated
Not Applicable
Oocyte CryopreservationFertilityNCT01232972Northwell Health23
Completed
Not Applicable
Oocyte Cryopreservation: Slow Cooling Versus Vitrification Techniques on Oocyte SurvivalInfertilityNCT00602966UConn Health14
Completed
Not Applicable
Oocyte Cryopreservation: The Impact of Cryopreservation on the Meiotic Spindle and Mitochondria of Human Oocytes.InfertilityNCT00716118West Coast Fertility Centers20
Recruiting
Not Applicable
Cryopreservation of Ovarian TissueCancerRisk of Premature Ovarian FailureFertility PreservationNCT01558544Weill Medical College of Cornell University300