Continuous Noninvasive Estimation of Intracranial Pressure to Assess Ventriculoperitoneal Shunt Malfunction in Patients With Hydrocephalus
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 163
- 主要终点
- The presence or absence of ventriculoperitoneal shunt malfunction in patients with hydrocephalus
研究概览
简要总结
Using a pulse oximeter, we have developed an algorithm that estimates intracranial pressure (ICP) based on patients who have had traumatic brain injuries. Patients with hydrocephalus are typically treated with a shunt in order to reduce ICP. At times the shunt can malfunction. We believe that our algorithm will help identify when a hydrocephalus patient's shunt has malfunctioned.
详细描述
A malfunctioning ventriculoperitoneal (VP) shunt will typically cause a rise in intracranial pressure, which can be difficult to identify without costly imaging. Novel, state-of-the art machine learning techniques can be leveraged to develop an algorithm that noninvasively estimates intracranial pressure. The resulting algorithm will accurately determine the presence or absence of ventriculoperitoneal shunt malfunction in patients with hydrocephalus.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 31 Days 至 35 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 31 days - 35 years
- •Patients seen at Children's Hospital Colorado Neurosurgery clinic, Emergency Department or on an inpatient service
- •Either hydrocephalus patients with a VP shunt in place (with or without suspicion of VP shunt malfunction), or patients with no known intracranial pathology.
排除标准
- •Pregnant patients
- •Incarcerated patients
- •Patients who object at any time to participating in the study.
结局指标
主要结局
The presence or absence of ventriculoperitoneal shunt malfunction in patients with hydrocephalus
时间窗: baseline
The algorithm development
次要结局
未报告次要终点