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Clinical Trials/NCT00279656
NCT00279656
Completed
Phase 4

Collaborative Approach to Improve the Quality of Medicines Use in Elderly Inpatients - Randomized Controlled Trial

Université Catholique de Louvain1 site in 1 country180 target enrollmentNovember 2003

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Frail Elderly Inpatient
Sponsor
Université Catholique de Louvain
Enrollment
180
Locations
1
Primary Endpoint
Appropriateness of prescribing (using the Medication Appropriateness Index, the Beers criteria, and the ACOVE criteria of underuse) on admission, at discharge, and 3 months post-discharge
Status
Completed
Last Updated
20 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the impact of a collaborative approach (geriatric care involving the collaboration with a clinical pharmacist) to optimize the prescription of medicines for elderly inpatients.

Detailed Description

Widespread evidence reveals frequent inadequate use of medicines in elderly patients. This includes inappropriate prescribing (overuse, underuse, misuse) that can lead to adverse drug events and drug-related admissions to hospital. In addition, when a patient is transferred from acute care settings to ambulatory care settings, discrepancies in medicines used often occur and can be hazardous. Despite this, only limited data exist on the effectiveness of optimization strategies targeted at frail elderly inpatients. Comparison: elderly inpatients receiving geriatric evaluation and management (GEM) care versus elderly inpatients receiving pharmaceutical care in addition to GEM care.

Registry
clinicaltrials.gov
Start Date
November 2003
End Date
June 2005
Last Updated
20 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Patient admitted on the acute geriatric unit of the university teaching hospital Mont-Godinne, Belgium

Exclusion Criteria

  • a terminal illness and life expectancy of less than 3 month
  • expected length of stay of 2 days or less
  • transfer from another unit where the patient had already been cared for by a GEM team
  • refusal to participate
  • inclusion during previous admission
  • no time for the clinical pharmacist to compound the abstracted chart within 3 days of admission

Outcomes

Primary Outcomes

Appropriateness of prescribing (using the Medication Appropriateness Index, the Beers criteria, and the ACOVE criteria of underuse) on admission, at discharge, and 3 months post-discharge

Secondary Outcomes

  • Polymedication on admission, at discharge, and 1,3,12 months after discharge
  • Mortality, readmission to hospital and visit to the emergency department 1,3,12 months after discharge
  • Satisfaction with information received on medicines

Study Sites (1)

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