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临床试验/NCT06381414
NCT06381414招募中不适用

Childhood Early Oral Aging Syndrome: Prevalence, Associated Etiological Factors, and Consequences on Vertical Dimension of Occlusion (VDO): A Cross-Sectional Study

University of Nove de Julho1 个研究点 分布在 1 个国家目标入组 183 人开始时间: 2024年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
183
试验地点
1
主要终点
Presence of Enamel Defects

研究概览

简要总结

The Early Oral Aging Syndrome (EOAS) is a broad concept concerning changes in oral health caused by systemic diseases of different origins, which are related to the current lifestyle in the pediatric population. Enamel defects associated with intrinsic and extrinsic factors promote the acceleration of dental structure loss in an early manner, causing impairment of function, aesthetics, and quality of life. In this context, this study aims to identify the prevalence of early childhood tooth wear and its severity using the Early Childhood Oral Aging Syndrome (EOAS) index as a diagnostic and epidemiological survey instrument, considering current alterations found in the pediatric population and verifying possible factors associated with each severity level. Participants aged 3 to 6 years old, enrolled in the pediatric dentistry clinic of the University Nove de Julho, will be selected. Children with imperfect amelogenesis and dentinogenesis, genetic syndromes, and undergoing orthodontic treatment will be excluded from the research. A questionnaire on general health, sleep quality, nutrition, hygiene habits, and parafunctional habits will be administered. Subsequently, a clinical examination will be conducted using the new Early Childhood Oral Aging Syndrome (EOAS) index with scores ranging from 0 to 3 to assess dental wear and dental management, and scores I to III that should be used concomitantly in cases of enamel defects presence, in addition to measuring the Vertical Dimension of Occlusion (VDO). EOAS scores will be computed and statistically analyzed for deciduous dentition with a significance level of P<0.05.

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Cross Sectional

入排标准

年龄范围
3 Years 至 6 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Children from three to six years of age with complete deciduous teeth;
  • Children regularly enrolled for dental care at the Uninove pediatric dentistry clinic

排除标准

  • Children with amelogenesis or dentinogenesis imperfecta
  • Children undergoing orthodontic treatment
  • Children with a genetic syndrome

结局指标

主要结局

Presence of Enamel Defects

时间窗: Baseline

CEOAS I- Presence of PMH - Demarcated opacities CEOAS II - Presence of PMH - Post-eruption fractures CEOAS III - Presence of fluorosis

Assessment of Tooth Wear and Dental Management

时间窗: Baseline

CEOAS 0 - Absence of signs CEOAS 1 - Mild: Presence of clinical signs in reversible stages, without sensitivity. Such cases require follow-up. CEOAS 2 - Moderate: Presence of advanced signs with sensitivity and compromised function. Such cases require restorative treatment and management of the sensitivity. CEOAS 3 - Severe: Presence of severe signs with pulp involvement and the risk of the loss of the tooth. Such cases require more invasive and rehabilitative treatment.

Vertical Dimension of Occlusion

时间窗: Baseline

The VDO measurement will be carried out with the participant sitting, head aligned with the body and gaze fixed on a specific point. Measurements will be taken in centric occlusion and will be done with the aid of a digital caliper: The following distances will be measured with the aid of a digital caliper: 1° Distance from the corner of the lip to the corner of the eye; 2° Distance from the base of the nose to the chin.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sandra Kalil Bussadori

Principal Investigator

University of Nove de Julho

研究点 (1)

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