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临床试验/CTRI/2025/02/080014
CTRI/2025/02/080014已完成不适用

ANALGESIC EFFICACY OF INTRAVENOUS IBUPROFEN WITH TRAMADOL AND INTRAVENOUS PARACETAMOL WITH TRAMADOL FOR REDUCING POST OPERATIVE PAIN IN PATIENTS UNDERGOING LOWER ABDOMINAL SURGERIES FOLLOWING SUBARACHNOID BLOCK - A RANDOMISED CONTROL TRIAL

Varun S1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2025年2月9日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80
试验地点
1
主要终点
VAS Score

研究概览

简要总结

Postoperative pain management is a critical aspect of patient care aimed at alleviating discomfort and facilitating recovery after surgery. Effective pain management involves a multidisciplinary approach, combining pharmacological and non-pharmacological interventions. Analgesic medications, such as opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen, are commonly used.

The choice of analgesics depends on factors such as the type and extent of surgery, patient preferences, and potential side effects. Balanced analgesia, which involves using multiple agents with different mechanisms of action, is often employed to optimize pain relief while minimizing adverse effects.

Non-pharmacological methods, including physical therapy, relaxation techniques, and patient education, complement drug therapy. Individualized pain management plans and regular assessment of pain levels contribute to enhancing postoperative recovery and patient satisfaction.

The relevance of this study lies in optimizing postoperative pain management, specifically for lower abdominal surgeries with subarachnoid block. The current state of knowledge indicates varying practices, and understanding the comparative efficacy of IV ibuprofen with tramadol and IV paracetamol with tramadol can contribute to refining treatment protocols.

The research question stems from a need for evidence-based approaches in pain management. Gaps in knowledge exist due to limited conclusive data on the comparative effectiveness of these analgesic combinations for this specific surgical context. This study aims to address this gap and provide valuable insights into selecting the most effective analgesic regimen.

This study is essential for improving clinical decision-making, tailoring analgesic strategies, and ultimately enhancing patient outcomes in a specific surgical population where pain management is crucial for recovery and overall well-being.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Age from 18 to 60 years Both male and females.

排除标准

  • Failed Subarachnoid block Know allergy to any of the study drugs Hepatic and renal dysfunction Lower segment Caesarean section.

结局指标

主要结局

VAS Score

时间窗: 30 min, 4hrs, 8hrs,12 hrs,20 hrs and 24 hrs after surgery

Numerical rating scale

时间窗: 30 min, 4hrs, 8hrs,12 hrs,20 hrs and 24 hrs after surgery

次要结局

  • Side effects(Duration of pain relief)

研究者

发起方
Varun S
申办方类型
Other [Self funding]
责任方
Principal Investigator
主要研究者

VARUN S

Dept of Anaesthesiology

研究点 (1)

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