Immune profiling of tumor and blood of patients with nasopharyngeal cancer

• Conditions: asopharynx cancer; nasopharyngeal carcinoma

• Registration Number: NL-OMON51134
• Lead Sponsor: Select

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

• Age >=18 years
• Able to understand the written information and able to give informed consent
• Should have histologically confirmed NPC
• Planned treatment with CR for locoregionally advanced NPC

Exclusion Criteria

• Unable to draw blood for study purposes
• Any coexisting condition which needs immediate treatment and which might
affect the results of the study

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>• Systemic immune parameters and their correlation to recurrence free survival<br /><br>and EBV titers<br /><br>• Local immune parameters and their correlation to recurrence free survival<br /><br>and EBV titers</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• Differences in systemic and local immune markers between primary and<br /><br>recurrent NPC<br /><br>• Kinetic changes in systemic and local immune parameters upon treatment<br /><br>• Correlation between systemic and local immune parameters</p><br>