pH Modulation And Salivary Clearance Rate Of Different Antitussive Lozenges In Adults: A Randomized Clinical Trial

Anti-tussive lozenges are often consumed by individuals suffering from sore throat and upper respiratory tract infections due to their cough suppressant and soothing effect on the oro-pharynx. There is indiscriminate use of lozenges due to their easy availability and affordability. The active ingredients in most of these lozenges are amylmetacresol, dichlorobenzyl alcohol and/or dextromethorphan and they impart an unpleasant taste. In order to make the lozenges palatable, large amounts of sugars are added to them. Besides sugars, these lozenges also contain acids that contribute to their inherent pH.Hence the present study is conducted To compare the salivary pH and oral sugar clearance of 4 different commercially available Anti-tussive lozenges.

Methodology: Forty subjects aged 18-35 years were selected randomly. Four different commercially available anti-tussive lozenges Vicks, Strepsils, Koflets, Tus Q  were given to subject. Salivary pH values and salivary sugar clearance rates are assessed at baseline before the consumption of lozenges and then 5, 10, 15, 20, and 30 min after consumption.