NCT01073111
撤回
不适用
Assessment of Neointimal Stent Strut Coverage and Endothelial Function After Second Generation Drug-Eluting Stent Systems
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Coronary Artery Disease
- 发起方
- Hyogo Medical University
- 试验地点
- 1
- 主要终点
- To compare coronary endothelial function after primary angioplasty.
- 状态
- 撤回
- 最后更新
- 7年前
概览
简要总结
The purpose of this study is to compare coronary endothelium function in patients with a zotarolimus-eluting versus a sirolimus-eluting or a everolimus-eluting stents with optical coherence tomography, vasoconstriction in response to acetylcholine, and coronary biomarker level.
研究者
Kenichi Fujii
Assistant Professor
Hyogo Medical University
入排标准
入选标准
- •Significant coronary de novo lesion (\> 70% by quantitative angiographic analysis)
- •Patients with stable or acute coronary syndrome considered for coronary revascularization
- •Reference vessel diameter of 2.5 to 3.5 mm by operator assessment
排除标准
- •Contraindication to anti-platelet agents
- •Ostial lesion within 5 mm from ostium
- •Different DES in other vessel simultaneously
- •Creatinine level 2.5 mg/dL
- •Left main stenosis more than 50%.
- •vein graft lesion
- •Triple vessel disease with stenosis more than 50% in 3 epicardial coronary arteries
- •Life expectancy 1 year
- •Reference vessel \< 2.5 mm or \> 4.0 mm diameter by visual
- •Long lesion that require more than three stents
结局指标
主要结局
To compare coronary endothelial function after primary angioplasty.
时间窗: 6 months and 12 months
To compare the presence of neointimal stent strut coverage via optical coherence tomography.
时间窗: 6 months and 12 months
To compare the serum biomarker levels measured in coronary artery blood.
时间窗: 6 months and 12 months
研究点 (1)
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