COMPARISON OF EPIDURAL(OUTSIDE SPINAL CORD)DEXAMETHASONE (STEROID)AND EPIDURAL MORPHINE(OPIOID)FOR POST OPERATIVE PAIN RELIEF IN TOTAL ABDOMINAL HYSTERECTOMY(REMOVAL OF UTERUS)

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/11/038020
• Lead Sponsor: VINAYAKA MISSIONS KIRUPANANDA VARIYAR MEDICAL COLLEGE AND HOSPITALS

Brief Summary

60 patients undergoing total abdominal hysterectomy under epidural anaeshesia will be recruited for the study. They will be randomized into two groups. One group will receive 4 mg morphine in 2 ml normal saline as an additive to    8 ml 0.5 % bupivacaine and the other group will receive 8 mg dexamethasone as an additive to 8 ml 0.5 % bupivacaine. The duration of postoperative analgesia will be assessed using visual analogue scale and the time of administration of first rescue analgesic will be noted and compared in both groups. Adverse effects will also be monitored.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-10-11
• Study Start: 2021-11-21

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

ASA 1 AND 2 PATIENTS UNDERGOING TOTAL ABDOMINAL HYSTERECTOMY UNDER EPIDURAL ANESTHESIA.

Exclusion Criteria

PATIENTS WHO ARE NOT WILLING FOR TRIAL, ALLERGIC TO DRUGS USED IN THE TRIAL, ASA GRADE 3 & 4, PATIENTS WHO ARE CONTRAINDICATED FOR EPIDURAL ANESTHESIA, PATIENTS REQUIRING GENERAL ANESTHESIA.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TO DETERMINE THE POSTOPERATIVE ANALGESIC EFFICACY OF EPIDURAL DEXAMETHASONE AND EPIDURAL MORHINE AS ADDITIVES TO BUPIVACAINE USING VISUAL ANALOG SCALE	POST OPERATIVE ANALGESIA WILL BE ASSESSED UPTO 24 HOURS

Secondary Outcome Measures

Name	Time	Method
TO ASSESS THE ADVERSE EFFECTS OF EPIDURAL DEXAMETHASONE AND MORPHINE	ADVERSE EFFECTS WILL BE MONITORED FOR 24 HOURS

Trial Locations

Locations (1)

VINAYAKA MISSIONS KIRUPANANDA VARIYAR MEDICAL COLLEGE AND HOSPITALS; 🇮🇳 Salem, TAMIL NADU, India

VINAYAKA MISSIONS KIRUPANANDA VARIYAR MEDICAL COLLEGE AND HOSPITALS

🇮🇳Salem, TAMIL NADU, India

PRIYANKA CHANDRAN

Principal investigator

9789092597

CPRIYANKA55@GMAIL.COM