Magneto-encephalography (MEG) to image the brain’s role in the analgesic effects of Spinal Cord Stimulation (SCS), an explorative study

Recruiting

• Conditions: neuropathic pain

• Registration Number: NL-OMON26558
• Lead Sponsor: Erasmus University Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

•Over 18 years,
•SCS for at least 3 months,
•Stable response to stimulation,
•Pulse generator suitable for burst stimulation,
•Active tip of the implanted electrode at spinal level Th8 or below,
•Pulse generator implanted in the lower body,
•Capable of participation: travelling to the institute and filling in the questionnaires

Exclusion Criteria

•Severe pain that is interfering with the pain that the SCS is used for,
•Hospitalised or another form of serious decline of general health

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences in the power in frequency bands in cortical pain processing areas as well as attention areas during resting-state MEG, under various stimulation settings and compared with control subjects.

Secondary Outcome Measures

Name	Time	Method
Differences in connectivity within cortical pain processing areas, and between pain processing areas and attention areas during resting-state MEG, under various stimulation settings and compared with control subjects.<br>Modulation of evoked responses to peripherally applied electrical stimulation, under various stimulation settings and compared with control subjects.