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临床试验/NL-OMON31892
NL-OMON31892尚未招募不适用

P-glycoprotein and Amyloid in M. Alzheimer - PIB PgP

niversitair Medisch Centrum Groningen0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • - Meet the NINCDS-ADRDA criteria for probable Alzheimer's disease
  • - Mild form of dementia (MMSE 19-22)
  • - Older than 50 years
  • Healthy controls do not meet NINCDS-ADRDA or MCI criteria.

排除标准

  • - Use of medication that could influence Pgp function, e.g. digoxin, cyclosporin, amiodarone, steroïds, quinidin, colchicin, etoposide, antiestrogensn and atorvastatin.
  • - Vasculair braindisease or otherwise braindiseases which could influence cerebral metabolism or perfusion.
  • - Significant kidney or liverdisase.
  • - Neurological symptoms not in agreement with a diagnosis of Alzheimer's disease.
  • - Pregnancy.
  • - Prior (excessive) radiation exposure in the same year (including radiological assistants or nuclear medicine employees).

研究者

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