Influence of the transcutaneous vagus nerve stimulation on the pupillary light reflex
Not Applicable
- Conditions
- Healthy Volunteers
- Registration Number
- DRKS00003316
- Lead Sponsor
- cerbomed GmbH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
healthy volunteers
written informed consent form after volunteer information
healthy in terms of medical history
Exclusion Criteria
anatomical and pathological abnormalities
previous eye surgeries
any medication (except contraceptives)
participation in a clinical study within the last 4 weeks prior inclusion
pregnant or breastfeeding women
indications that the participant is expected not to comply with the clinical investigation plan (e.g. lacking willingness to cooperate)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method parameters of the pupillary light reflex: initial pupil diameter, relative amplitude, constriction velocity<br>time of measurement: befor t-VNS (PRE), during t-VNS (PERI) and after t-VNS (POST)
- Secondary Outcome Measures
Name Time Method sensitive sensations (self-evaluation by the volunteer)<br>screening for vegetative symptoms (self-evaluation by the volunteer)<br>number of adverse events / incidents