To compare selective laser trabeculoplasty (SLT) with prostaglandin analogue as first line therapy in African Primary Open Angle Glaucoma (POAG) patients

niversity College London0 个研究点目标入组 571 人开始时间: 2015年12月14日最近更新: 2021年1月5日

适应症

试验速览

暂无简介。

•1. Consent to inclusion and participation in trial
•2. Characteristic glaucomatous changes in the optic disc. The presence of a focal or diffuse area of optic disc rim loss, so that the neuroretinal rim tissue in any quadrant is less than 5% of the disc diameter in that meridian. Extensive loss of neuroretinal rim tissue with marked optic disc cupping giving a cup disc ratio greater than 0.6
•3. A measured intraocular pressure greater than or equal to 21 mmHg and less than or equal to 30mmHg on at least one visit before the time of entry into the study as measured by Goldmann applanation tonometry
•4. Adequate visualization of angle structures (i.e. clear media and cooperative patient)
•5. Black African patients

•1. Unwillingness to participate in the study
•2. Inability/unwillingness to give informed consent
•3. Unwillingness to accept randomisation
•4. Patient less than 20 years of age
•5. Anterior segment neovascularisation
•6. Past trauma to the eye or ocular adnexae
•7. Retinal or optic nerve neovascularisation
•8. Aphakia or pseudophakia
•9. Previous ocular surgery Evidence of ocular disease other than glaucoma that might affect the measurements of IOP, assessment of visual function, visual field testing would likely require cataract surgery within 12 months of randomization on systemic medications known to IOP (e.g. steroids) Pregnancy or female of childbearing age who may be pregnant at time of treatment (LMP).
•10. Anyone who is not Black African race

发起方

niversity College London