The effects and mechanism of whole body vibration training on muscle performance, physical performance and balance in the older people with age-related loss of muscle mass

Not Applicable

Completed

• Conditions: Sarcopenia; Musculoskeletal Diseases

• Registration Number: ISRCTN63583948
• Lead Sponsor: The Hong Kong Polytechnic University

Brief Summary

1. 2016 results in: https://www.ncbi.nlm.nih.gov/pubmed/27578535 2. 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/30305044 (added 16/07/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-12-30
• Study Start: 2017-01-16
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Aged 65 years and over
2. Skeletal mass index less than 8.87kg/m2 and 6.42kg/m2

Exclusion Criteria

1. Participants with metal implants
2. Severe heart problem
3. Neurodegenerative diseases
4. Peripheral vascular disease
5. Vestibular disorders
6. Severe osteoporosis with fractures within one year prior to the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Muscle mass (cross-sectional area of vastus medialis) was measured by ultrasound at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks<br> 2. Muscle strength (peak torque of knee extension) was measured by Cybex with isokinetic (180 and 60 degrees per second) and isometric (knee flexed at 90 degrees) contractions at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks<br> 3. Physical performance was measured by five-repetition sit-to-stand, timed-up-and-go test and 10-meter walking test at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Proprioception was measured by knee joint repositioning test at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks<br> 2. Balance was measured by tandem, one-leg stand with eyes open and closed at baseline, 6 (18 training sessions), 12 (36 training sessions), 18 and 24 weeks<br> 3. Voluntary activation was measured by twitch interpolation test at baseline and 12 weeks (36 training sessions)<br>