The Effect of Phosphatidylserine on Time Trial Performance in Trained Male Cyclists
- Conditions
- The Focus of the Study is to Investigate the Effects of Phosphatidylserine Supplementation on Exercise Physiology and Cycling Time-trial Performance
- Interventions
- Dietary Supplement: Phosphatidylserine
- Registration Number
- NCT04967404
- Lead Sponsor
- Mark Glaister
- Brief Summary
Phosphatidylserine is a phospholipid found in high concentrations in the brain and nervous tissues along with naturally occurring in many foods. It has been extensively studied for its effects on improving cognitive function, learning, memory and alleviating stress. However, more recently it has been proposed that phosphatidylserine could improve exercise capacity. The mechanisms of proposed action are difficult to distinguish because of the limited research and therefore the purpose of this study is to identify the proposed mechanism of action of phosphatidylserine supplementation and to establish whether these mechanisms will have an effect on time trial performance in trained male cyclists.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 20
- Cyclists
- Maximum oxygen uptake of at least 55 mL/kg/min
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Maltodextrin, 800 mg per day, 10 days Phosphatidylserine - Phosphatidylserine, 800 mg per day, 10 days Phosphatidylserine -
- Primary Outcome Measures
Name Time Method 30 minute cycling time-trial power output on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Mean power output
- Secondary Outcome Measures
Name Time Method Rating of perceived exertion at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Evaluated using a 15-point (6-20) scale
Oxygen consumption at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Evaluated using an online breath-by-breath gas analyser
Breathing frequency at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Evaluated using an online breath-by-breath gas analyser
Blood glucose concentration at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Obtained via capillary puncture and analysed using an automated analyser
Minute ventilation at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Evaluated using an online breath-by-breath gas analyser
Blood lactate concentration at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Obtained via capillary puncture and analysed using an automated analyser
Heart rate at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Evaluated using a heart rate monitor
Respiratory exchange ratio at four different exercise intensities (40, 50, 60 and 70% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer From baseline to 11 days post supplementation Evaluated using an online breath-by-breath gas analyser