Effect of low calorie diets on inflammation in metabolic syndrome

Not Applicable

Conditions: metabolic syndrome disease.
Metabolic syndrome
E88.81

Registration Number: IRCT20150909023957N7

Lead Sponsor: Vice Chancellor for Research, Isfahan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 70

Inclusion Criteria

Patients with Metabolic Syndrome
Age 25- 60 years
25 =BMI = 40 kg/m2
Body weight more than 5 kg has not changed during the last 3 months.
No fasting for 3 months prior to the beginning of the study
People who are willing to cooperate and answer questions and conduct their tests after explaining the work.

Exclusion Criteria

Smoker
History of cardiovascular, pulmonary, renal, thyroid disorders, digestive and liver problems such as hepatitis and ...
Follow a special diet
Severe physical activity
People who have been using drugs that have an effect on weight loss, lipid or glucose metabolism, inflammatory condition and coagulation factors over the past 6 months.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum High- Sensitivity- C- Reactive Protein (Hs- CRP). Timepoint: Two times, before and after dietary intervention. Method of measurement: Serum hs- CRP concentration was assayed using ELISA kits (LDN, Nordhorn, Germany).;Fibrinogen. Timepoint: Two times, before and after dietary intervention. Method of measurement: Fibrinogen was also measured using immunoturbidimetry tests (Pars Azmoon. Co., Iran).;PT (Prothrombine Time). Timepoint: Two times, before and after dietary intervention. Method of measurement: PT was tested using (PT- based) Prothrombin Clot-Based Assay (sec) method.;A-PTT (activated limited thromboplastin time). Timepoint: Two times, before and after dietary intervention. Method of measurement: a- PTT was tested using (PT- based) Prothrombin Clot-Based Assay (sec) method.

Secondary Outcome Measures