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Water-filtered Infrared-A Radiation in Patients With Hand Osteoarthritis

Not Applicable
Recruiting
Conditions
Hand Osteoarthritis
Interventions
Device: water-filtered Infrared-A radiation
Registration Number
NCT06329219
Lead Sponsor
Charite University, Berlin, Germany
Brief Summary

The aim of this clinical trial is to evaluate the effects of water-filtered Infrared-A radiation on patients suffering from hand osteoarthritis. The main questions it aims to answer are:

* Does water-filtered Infrared-A radiation reduce pain and improve the function of finger joints over time?

* Are patients satisfied with the treatment results when compared to those who were on a wait-list?

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
70
Inclusion Criteria
  • Diagnosis of finger polyarthritis (confirmed by a specialist, radiological findings available)
  • Local pain for more than 50% of the day in the past 3 months.
  • Subjective pain intensity of local pain in the last 24 hours on a VAS scale of 0 to 10 being >4.
  • No planned local treatment in the next 6 months.
  • No planned intra-articular injections within the next 6 months.
  • The patient must be able to understand the study explanations and appropriately follow the instructions of the investigating physician.
Exclusion Criteria
  • Chronic inflammatory joint diseases.
  • Poor general health.
  • Febrile diseases.
  • Fibromyalgia syndrome.
  • Psychotic disorders.
  • Severe comorbidities.
  • Acute unclear skin diseases.
  • Heat urticaria.
  • Painful diseases/diagnoses of the shoulder and/or arm.
  • Lymphatic vessel diseases (lymphedema, lymphangitis).
  • Porphyria.
  • Pain-associated diseases/diagnoses of the shoulder and/or arm.
  • Intra-articular injections or arthroscopies within the last 3 months.
  • Previous or planned surgical procedure on the affected joints in the last 8 weeks or in the upcoming 6 months.
  • Intake or application of photosensitizing drugs or extracts (e.g., porphyrins, tetracyclines, sulfonamides, psoralenes, St. John's wort).
  • Systemic medication with glucocorticoids or immunosuppressants.
  • Pain medication with opioid analgesics.
  • Known pregnancy.
  • Concurrent participation in another clinical trial.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Radiationwater-filtered Infrared-A radiationParticipants in the intervention group each receive a hyperthermia device for water-filtered Infrared-A radiation.
Primary Outcome Measures
NameTimeMethod
Pain in the finger joints on visual analogue scaleBaseline, 12 weeks

Average pain in the finger joints over the last 7 days after 12 weeks compared to baseline on the Visual Analog Scale (VAS, 0-100mm) compared to the waiting list control group.

Secondary Outcome Measures
NameTimeMethod
Hand DynamometerBaseline, 6 weeks, 12 weeks, 24 weeks

Grip strength measured using a Hand Dynamometer (SAEHAN Corporation)

Disabilities of Arm, Shoulder and Hand (DASH) questionnaireBaseline, 6 weeks, 12 weeks, 24 weeks

Assessing full scale, range 0-100, higher score meaning a better outcome

Short Form (SF)-36 Health Survey (SF-36)Baseline, 6 weeks, 12 weeks, 24 weeks

Assessing full scale, range 0-100, higher score meaning a better outcome

Functional Index for Hand OsteoArthritis (FIHOA)Baseline, 6 weeks, 12 weeks, 24 weeks

Assessing functional impairment, scoring from 0 (no functional impairment) to 30 points (maximal impairment).

Pain Self-Efficacy QuestionnaireBaseline, 6 weeks, 12 weeks, 24 weeks

Assessing full scale, range 0-100, higher score meaning a better outcome

Hospital Anxiety and Depression Scale (HADS)Baseline, 6 weeks, 12 weeks, 24 weeks

Assessing full scale, range 0-100, higher score meaning a better outcome

Pain medication (number per day)Baseline, 6 weeks, 12 weeks, 24 weeks

Documenting changes in pain medication and pain medication on demand

Tolerability of the interventionBaseline, 6 weeks, 12 weeks, 24 weeks

Monitoring tolerability of the intervention (5-point Likert scale, 1=very good tolerability to 5=very bad tolerability)

Trial Locations

Locations (1)

Charité - Universitätsmedizin Berlin at the Department of Internal and Integrative Medicine, Immanuel Krankenhaus Berlin

🇩🇪

Berlin-Wannsee, Berlin, Germany

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