FCM Analysis GR in Steroid-Treatment Patients
- Conditions
- Healthy
- Registration Number
- NCT00600652
- Lead Sponsor
- Changhai Hospital
- Brief Summary
Monitoring the GR with a GR-MoAb and FITC-Dex probes by FCM would be useful and convenient in determination GR before the steroid treatment in clinical, especially in steroid resistant states, in order to design more efficient clinical treatment protocols.
- Detailed Description
In order to assess the efficacy of this method, 100 patients with nephrotic syndrome and systemic lupus erythematosus receiving sufficient prednisolone thereafter and 50 age- and sex-matched normal controls will be studied.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
- Clinical diagnosis of SLE and NS
Exclusion Criteria
- Receiving hormone replacement therapy or had received hormone replacement therapy in three months before start of the study
- Received drugs or drinks containing alcohol within one month
- Having symptom such as infection
- Supersensitivity and endocrine disturbance.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method