NCT00595894已完成不适用
RA Comorbidity: Bone Health in Men and African Americans
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,745
- 试验地点
- 1
- 主要终点
- Bone mineral density
研究概览
简要总结
The objective of the proposed study is to assess bone health and determinants of bone health among select subpopulations of rheumatoid arthritis patients.
详细描述
The overall hypothesis of this study is that osteopenia and/or osteoporosis are common among African Americans and men with rheumatoid arthritis and there are identifiable genetic and environmental factors contributing to the pathogenesis of bone loss in these groups.
The Specific Aims of the study are to:
- Determine baseline hip and lumbar spine bone density (BMD) values and osteopenia/osteoporosis prevalence among African American men and women with early RA and among male veterans with established RA.
- Identify environmental factors and candidate alleles, which confer increased risk of reduced baseline BMD loss over time among African American men and women with early RA and among male veterans with established RA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of rheumatoid arthritis per ACR guidelines
排除标准
- •Patients with diagnosis > 2yrs (CLEAR study)
结局指标
主要结局
Bone mineral density
时间窗: baseline and at 5 years disease
Bone mineral density (BMD) test measures calcium and other minerals in bone. Bones containing more minerals are denser, so they tend to be stronger and less likely to break.
次要结局
未报告次要终点
研究者
研究点 (1)
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