Determining liver fat content with MRT scans to analyze the effect of liver activity on the basal metabolic rate
- Conditions
- Impact of liver activity on basal metabolic rate
- Registration Number
- DRKS00013549
- Lead Sponsor
- ehrstuhl für Molekulare Ernährungsmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Written consent form,
European;
BMI 18-35 kg/m²,
participation in the enable project Z
missing consent form,
active smoker,
chronic diseases: chronic infection (e.g. HIV), liver diseases (e.g. HBV, HCV); diabetes mellitus; untreated endocrinologic diseases (e.g. thyrotoxicosis or hypothyroidism); autoimmune disease; heart attack, heart disease, cancer or stroke within the last three years; pacemaker; high blood pressure (>150/95 mmHg); circulatory disorder; kidney dialysis; chronic lung disease; gastric ulcer; Parkinson's disease; severe psychological or neurological disorder within the last three years; blood transfusion; outpatient care; unintended weight loss (>5% in the last three months);
Contraindication for MRT: pacemaker; implanted defibrillator; artificial cardiac valve; cardioseal; aneurisma-clips (not MR compatible); implanted magnetic metal part;cochlear implant; metal shiver; shell splinter; acupuncture needle; insulin pump; piercings (non removeable); lung diseases; diseases with the central nervous system; pregnant or breast feeding women; claustrophobia; active participation at other medical trials
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identifying the impact of liver actitvity (determined by MRT scans) on the resting metabolic rate (determined by indirect calorimetry).
- Secondary Outcome Measures
Name Time Method Identification of correlation between liver fat content, visceral und subcutanous fat. Visceral and subcutanous fat are determined by MRT scans.