Effect of trehalose eye-drops on the maintenance of filtration bleb after trabeculectomy - postoperative instillation of trehalose after trabeculectomy

A beneficial effect of trehalose ophthalmic drops could not be confirmed during the observation period in this study. This may be due to the fact that intraoperative mitomycin C had already been applied to all patients in this study, which itself has a strong effect of maintaining filtration vesicles and lowering intraocular pressure, which may have masked any effect of the addition of trehalose on inhibiting fibroblast proliferation. A longer study period is needed in the future.