Effects of Laughter Yoga on Hemodialysis Patients' Plasma-Beta Endorphin Levels, Pain Levels and Sleep Quality

Not Applicable

Completed

• Conditions: Laughter Yoga; Hemodialysis Patients
• Interventions: Behavioral: Laughter yoga

• Registration Number: NCT04175652
• Lead Sponsor: Istanbul Sabahattin Zaim University

Brief Summary

This study aimed to assess the effectiveness of laughter yoga on HD patients' plasma beta endorphin levels, pain levels and sleep quality.

Detailed Description

While there are studies conducted with laughter yoga on different patient groups in Turkey, no studies have been found on hemodialysis patients specifically. For this reason, it was thought that studies are needed which will prove the effect of laughter yoga practices on the plasma beta-endorphin levels, pain levels and sleep quality of hemodialysis patients.

Study Timeline

• Study Start: 2017-11-15
• Primary Completion: 2018-06-15
• Study Completion: 2018-10-31
• Status Verified: 2019-11
• Study First Submitted: 2019-11-21
• Study First Submitted QC: 2019-11-21
• Last Update Submitted: 2019-11-21
• Study First Posted: 2019-11-25
• Last Update Posted: 2019-11-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• receiving treatment in a dialysis center
• must be between 18 and 80 years old and willing to participate in the study
• receiving HD treatment at least twice a week for a month or longer
• having a pain level and above
• level of 5 above according to the Pittsburgh Sleep Quality Index.

Exclusion Criteria

• not taking any medicine for sleeping disorder
• not having any visual, hearing or communication impairments
• not having any mental disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Laughter yoga group, group doing laughter yoga	Laughter yoga	The duration of the laughter yoga was 30 minutes and a total of 16 sessions were performed on a twice-weekly basis.

Primary Outcome Measures

Name	Time	Method
Beta-endorphin Level	8 week	Blood samples were taken from all individuals who participated in the study, through their AVF fistulas by using 3.5 mL gel-based tubes and following antiseptic rules. Blood samples which were fully coagulated were centrifuged at 1500xg for 10 minutes and serums were obtained. The serum samples were separated into portions and kept at -80 °C until the analysis.
Visual Analog Scale	8 week	The patients were asked to mark their level of pain during relaxation or activities on a 10 cm vertical or horizontal line. In addition, there were forms which were numbered from 1-10 or from 1-100. The number 0 is found at the beginning of the line, and the number 10 is located at the end of the line. A value of 0 shows that there is no pain, and the value 10 expresses unendurable pain. GAS is a common scale in the assessment of pain level. A patient is asked to mark the perceived pain on this line, and the marked point is measured in cm
Pittsburgh Sleep Quality Index	8 week	The PSQI is a valid and consistent survey comprising of 19 questions to assess quality and amount of sleep and the existence of a sleep disorder and its level in the previous month. The scale was adapted into the Turkish language by Agargün et al. (1996). The scale consists of seven components that assess patients subjective sleep quality, sleep delay, use of sleeping medication and disfunction in daily activities. Each item scores in the range 0-3 points and the total score of the seven components gives the total PSQI score. The total score has a value between 0-21 and a high total score demonstrates a poor quality of sleep. A total PSQI score which is ≤5 indicates "good sleep", and a score which is \>5 indicates "poor sleep"

Trial Locations

Locations (1)

Istanbul Sabahattin Zaim University, Faculty of Health Sciences; 🇹🇷 Istanbul, Küçükçekmece, Turkey