Application of Antiosteoporosis Therapy in Osteolysis

Not yet recruiting

• Conditions: Complication; Limb; Fusion
• Interventions: Other: Anti-osteoporosis therapy

• Registration Number: NCT05617846
• Lead Sponsor: Henan Cancer Hospital

Brief Summary

To report the postoperative complications and limb function of patients with osteolysis after surgery for bone tumors of the extremities who received anti-osteoporosis therapy in Henan Cancer Hospital in the next 10 years.

Detailed Description

A total of 100 patients with osteolysis after surgery for bone tumors of the four extremities who received anti-osteoporosis treatment in Henan Cancer Hospital in the next 10 years were reported. The basic information, treatment methods, postoperative complications and limb function of these patients were collected.

Study Timeline

• Study First Submitted: 2022-10-31
• Study First Submitted QC: 2022-11-14
• Study First Posted: 2022-11-16
• Status Verified: 2023-08
• Last Update Submitted: 2024-01-16
• Last Update Posted: 2024-01-18
• Study Start: 2024-12-28
• Primary Completion: 2032-11-30
• Study Completion: 2032-11-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. No age restriction, male or female.
2. A subtype of bone tumor (including benign, malignant, and metastatic cancer) was confirmed in the pathology department of the research institution.
3. Received excision of bone tumor in research institution.

Exclusion Criteria

Not applicable.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Intervention group	Anti-osteoporosis therapy	Patients who received antiosteoporosis therapy after bone tumor resection

Primary Outcome Measures

Name	Time	Method
Complications	Collected from the beginning of treatment to 24 months after treatment.	The incidence of complications after anti-osteoporosis treatment was collected and the severity of complications was evaluated according to CTCAE5.0.
Limb function	Collected from the beginning of treatment to 24 months after treatment.	Limb function was assessed using the Musculoskeletal Oncology Society (MSTS) scoring scale for seven items, namely movement, pain, stability, deformity, strength, functional activity, and emotional receptiveness. The highest possible score is 35, with 5 points allocated to each project.

Trial Locations

Locations (1)

Department of Bone and Soft Tissue ,Henan Cancer Hospital; 🇨🇳 Zhengzhou, Henan, China