Prevention of nosocomial infections in Intensive Care
Suspended
- Conditions
- nosocomial infectionsIntensive Care antimicrobial prophylaxisprobiotic prophylaxiscross-over clinical trial
- Registration Number
- NL-OMON27737
- Lead Sponsor
- Maastricht University Medical Centre (MUMC)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 370
Inclusion Criteria
All consecutive patients admitted to the ICU who are older than 18 years and have an expected duration of mechanical ventilation of at least 48 hours, expected length of stay at the ICU of at least 72 hours or both.
Exclusion Criteria
previous admission to the ICU within 3 months, known hypersensitivity to the study medication, pregnancy, contra-indication for enteral feeding, perceived imminent death, and participation in another investigational study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of all infections occurring > 48 hours after admission at the ICU during the intervention and follow up period.
- Secondary Outcome Measures
Name Time Method - ICU and in-hospital mortality rate; <br /><br>- prevalence of antibiotic resistant microorganisms<br /><br>- additional and total antibiotic use.