Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis
- Registration Number
- NCT02914535
- Lead Sponsor
- Galapagos NV
- Brief Summary
The primary objective of this study is to observe the long-term safety of filgotinib in adults who have completed or met protocol specified efficacy discontinuation criteria in a prior filgotinib treatment study in ulcerative colitis (UC).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 1173
- Must have the ability to understand and sign a written informed consent form (ICF), which must be obtained prior to initiation of study procedures associated with this trial
- Must have enrolled in Gilead-sponsored UC parent protocol GS US 418-3898 or any other Gilead/Galapagos-sponsored filgotinib treatment study for UC
- Must have completed all required procedures or met protocol-specified efficacy discontinuation criteria in a prior filgotinib treatment study for UC
- Females of childbearing potential must have a negative pregnancy test at Day 1
- Female individuals of childbearing potential who engage in heterosexual intercourse must agree to use protocol specified method(s) of contraception for the duration described
- Willingness to refrain from live or attenuated vaccines during the study and for 12 weeks after last dose of study drug
Key
- Known hypersensitivity to the study drug
- Any chronic medical condition (including, but not limited to, cardiac or pulmonary disease, alcohol or drug abuse) that, in the opinion of the Investigator or sponsor, would make the subject unsuitable for the study or would prevent compliance with the study protocol
- Females of reproductive potential who are unwilling to abide by protocol-specified contraceptive methods as defined
- Use of prohibited medications as outlined in the protocol
NOTE: Other protocol defined Inclusion/ Exclusion criteria may apply.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Filgotinib 100 mg (blinded dosing) Filgotinib Filgotinib 100 mg + placebo to match filgotinib 200 mg for up to 336 weeks Filgotinib 200 mg (blinded dosing) Placebo Filgotinib 200 mg + placebo to match filgotinib 100 mg for up to 336 weeks Filgotinib 100 mg (blinded dosing) Placebo Filgotinib 100 mg + placebo to match filgotinib 200 mg for up to 336 weeks Placebo (blinded dosing) Placebo Placebo to match filgotinib 200 mg + placebo to match filgotinib 100 mg for up to 336 weeks Filgotinib 200 mg (open-label) Filgotinib Filgotinib 200 mg for up to 336 weeks Filgotinib 200 mg (blinded dosing) Filgotinib Filgotinib 200 mg + placebo to match filgotinib 100 mg for up to 336 weeks Filgotinib 100 mg (open-label) Filgotinib Filgotinib 100 mg for up to 336 weeks
- Primary Outcome Measures
Name Time Method Overall Safety Profile of Filgotinib Evaluated by Proportion of Participants Experiencing Adverse Events and Abnormal Clinical Laboratory Tests Up to 336 weeks plus 30 days
- Secondary Outcome Measures
Name Time Method Change From Baseline in Components of Mayo Clinic Score (MCS) Baseline and up to 336 weeks
Trial Locations
- Locations (323)
Cedars Sinai Medical Center
๐บ๐ธLos Angeles, California, United States
University of Miami Crohn's and Colitis Center
๐บ๐ธMiami, Florida, United States
Cordova Research Institute
๐บ๐ธMiami, Florida, United States
Massachusetts General Hospital - Crohn's and Colitis Center
๐บ๐ธBoston, Massachusetts, United States
Meritus Center for Clinical Research
๐บ๐ธHagerstown, Maryland, United States
Bodyclinic
๐ต๐ฑWarszawa, Poland
Centrum Medyczne Oporow
๐ต๐ฑWroclaw, Poland
Twoja Przychodnia-Szczecinskie Centrum Medyczne
๐ต๐ฑSzczecin, Poland
Municipal Non-profit Enterprise "Consultative and Diagnostic Center" of Pechersk District of Kyiv, Therapy Department
๐บ๐ฆKyiv, Ukraine
Niepubliczny Zaklad Opieki Zrodotnej VIVAMED Jadwige Miecz
๐ต๐ฑWarszawa, Poland
Gelre Hospital
๐ณ๐ฑApeldoorn, Netherlands
Krakowskie Centrum Medyczne Sp. z o.o
๐ต๐ฑKrakรณw, Poland
EUGASTRO GmbH
๐ฉ๐ชLeipzig, Germany
Delta Research Partners, LLC
๐บ๐ธMonroe, Louisiana, United States
Gastro One
๐บ๐ธGermantown, Tennessee, United States
Atlanta Gastroenterology Specialist, PC
๐บ๐ธSuwanee, Georgia, United States
Gastroenterology Associates Of Central Georgia, LLC
๐บ๐ธMacon, Georgia, United States
Florida Medical Clinic, P.A
๐บ๐ธZephyrhills, Florida, United States
South Denver Gastroenterology, PC
๐บ๐ธLone Tree, Colorado, United States
Investigative Clinical Research
๐บ๐ธAnnapolis, Maryland, United States
Center for Digestive Health Research
๐บ๐ธTroy, Michigan, United States
NY Scientific
๐บ๐ธBrooklyn, New York, United States
NYU Langone Long Island Clinical Research Associates
๐บ๐ธGreat Neck, New York, United States
San Antonio Military Medical Center
๐บ๐ธFort Sam Houston, Texas, United States
Digestive Health Specialists Of The Southeast
๐บ๐ธDothan, Alabama, United States
Florida Research Institute
๐บ๐ธLakewood Ranch, Florida, United States
VA Long Beach Healthcare System
๐บ๐ธLong Beach, California, United States
Gastrointestinal Specialists of Georgia
๐บ๐ธMarietta, Georgia, United States
Connecticut GI PC-Research Division
๐บ๐ธFarmington, Connecticut, United States
University of Iowa Hospitals and Clinics
๐บ๐ธIowa City, Iowa, United States
Gastroenterology Group of Naples
๐บ๐ธNaples, Florida, United States
Advanced Medical Research Center
๐บ๐ธPort Orange, Florida, United States
The University of Texas Health Science Center at Houston
๐บ๐ธHouston, Texas, United States
University Hospital Center Zagreb
๐ญ๐ทZagreb, Croatia
Rapid City Medical Center
๐บ๐ธRapid City, South Dakota, United States
Princess Alexandra Hospital
๐ฆ๐บWoolloongabba, Queensland, Australia
MHAT "Sveta Petka" AD
๐ง๐ฌVidin, Bulgaria
MHAT Sveti Pantaleymon- Pleven OOD
๐ง๐ฌPleven, Bulgaria
The Gordon and Leslie Diamond Health Care Centre
๐จ๐ฆVancouver, British Columbia, Canada
AKH-Medizinische Universitat Wien
๐ฆ๐นWien, Austria
DHAT Research Institute
๐บ๐ธGarland, Texas, United States
Mater Misericordiae Ltd
๐ฆ๐บSouth Brisbane, Queensland, Australia
Monash Medical Centre
๐ฆ๐บClayton, New South Wales, Australia
University of Calgary, Heritage Medical Research Clinic
๐จ๐ฆCalgary, Alberta, Canada
Texas Digestive Disease Consultants
๐บ๐ธSouthlake, Texas, United States
Allegiance Research Specialists, LLC
๐บ๐ธWauwatosa, Wisconsin, United States
"MDHAT Dr. St.Cherkezov" AD
๐ง๐ฌVeliko Tarnovo, Bulgaria
Spring Gastroenterology
๐บ๐ธThe Woodlands, Texas, United States
Nepean Hospital
๐ฆ๐บKingswood, New South Wales, Australia
Instituto Mรฉdico Cer
๐ฆ๐ทQuilmes, Argentina
Baylor College of Medicine - Baylor Medical Center
๐บ๐ธHouston, Texas, United States
University of Virginia Health System
๐บ๐ธCharlottesville, Virginia, United States
Gastroenterology Associates of Tidewater
๐บ๐ธChesapeake, Virginia, United States
G.E.P. Clinic, s r.o.
๐จ๐ฟPraha 3, Czechia
Medi Club Georgia LLC
๐ฌ๐ชTbilisi, Georgia
CUB Hopital Erasme
๐ง๐ชBrussel, Belgium
Centre Hospitalier Chretien (CHC) - Clinique Saint-Joseph
๐ง๐ชLiรจge, Belgium
CHU Amiens Picardie
๐ซ๐ทAmiens Cedex 1, France
CHU Hotel-Dieu
๐ซ๐ทNantes, France
CHU de Caen
๐ซ๐ทCaen Cedex 9, France
Hamilton Health Sciences Corporation, McMaster University Medical Centre
๐จ๐ฆHamilton, Ontario, Canada
CHU de Clermont-Ferrand - Hopital d'Estaing
๐ซ๐ทClermont-Ferrand, France
CHU de Dijon Bourgogne - Hopital Francois Mitterand
๐ซ๐ทDijon, France
Hopital Universitaire de Bicetre
๐ซ๐ทLe Kremlin Bicetre, France
Hepato-Gastroenterology HK, s.r.o.
๐จ๐ฟHradec Kralove, Czechia
Oblastni nemocnice Mlada Boleslav, a.s., nemocnice Stredoceskeho kraje, Gastroenterologicke oddeleni
๐จ๐ฟMlada Boleslav, Czechia
Centre Hospitalier Regional Universitaire de Lille
๐ซ๐ทLille, France
CHU de Toulouse - Hopital Rangueil
๐ซ๐ทToulouse, France
VGM Hospital Institute of Gastroenterology
๐ฎ๐ณCoimbatore, India
Centre for Liver Research & Diagnostics
๐ฎ๐ณHyderabad, India
Kasturba Medical College (KMC) Hospital
๐ฎ๐ณMangaluru, India
Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Kozponti Felnott Szakrendelo
๐ญ๐บBudapest, Hungary
Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital
๐ญ๐ฐShatin, Hong Kong
The Catholic University of Korea, St. Vincent's Hospital
๐ฐ๐ทSuwon-si, Gyeonggi-do, Korea, Republic of
Hospital Queen Elizabeth
๐ฒ๐พKota Kinabalu, Malaysia
Bnai Zion Medical Center
๐ฎ๐ฑHaifa, Israel
Yonsei University Health System, Severance Hospital
๐ฐ๐ทSeoul, Korea, Republic of
Yeungnam University Hospital
๐ฐ๐ทDaegu, Korea, Republic of
Shaare Zedek Medical Center
๐ฎ๐ฑJerusalem, Israel
Wakayama Medical University Hospital
๐ฏ๐ตWakayama-shi, Japan
Yonsei University Wonju Severance Christian Hospital
๐ฐ๐ทWonju, Korea, Republic of
Centrum Opieki Zdrowotnej Orkan-Med Stec-Michalska Sp. J.
๐ต๐ฑKsawerรณw, Poland
Academic Medical Center (AMC)
๐ณ๐ฑAmsterdam, Netherlands
PCR-Phylasis Clinicas Research S. de R.L. de C.V.
๐ฒ๐ฝCuautitlรกn Izcalli, Mexico
VITAMED Galaj i Cichomski spรณlka jawna
๐ต๐ฑBydgoszcz, Poland
Niepubliczny Zaklad Opieki Zdrowotnej ALL-MEDICUS
๐ต๐ฑKatowice, Poland
Centrum Innowacyjnych Terapii Sp. z o.o.
๐ต๐ฑPiaseczno, Poland
Ieda Hospital
๐ฏ๐ตToyota-shi, Japan
Gabinet Lekarski Dr. Hab. N. Med. Bartosz Korczowski
๐ต๐ฑRzeszรณw, Poland
Endocsopia Digestiva Centralizzata - ASST Fatebenefratelli Sacco, Ospedale Fatebenefratelli e Oftalmico
๐ฎ๐นMilano, Italy
Kangbuk Samsung Hospital
๐ฐ๐ทSeoul, Korea, Republic of
Hospital Pulau Pinang
๐ฒ๐พGeorge Town, Malaysia
Gastroenterologische Praxis Balsiger, Seibold und Partner
๐จ๐ญBern, Switzerland
Ivanto-Frankivsk Central City Clinic Hospital, Therapy Department #1. State Higher Education Institution Ivano-Frankivsk National
๐บ๐ฆIvano-Frankivsk, Ukraine
Municipal Institution of Health Care "Regional Hospital of War Veterans", Therapeutic Department No1
๐บ๐ฆKharkiv, Ukraine
Odesa Clinical Railway Hospital Branch of "Healthcare Center" of Public joint stock company "Ukrainian Railway"
๐บ๐ฆOdessa, Ukraine
Skane University Hospital
๐ธ๐ชMalmo, Sweden
Asan Medical Center
๐ฐ๐ทSeoul, Korea, Republic of
Ofuna Chuo Hospital
๐ฏ๐ตKamakura, Japan
Tokai University Hachioji Hospital
๐ฏ๐ตHachioji, Japan
Colo-proctology Center Matsushima Clinic
๐ฏ๐ตYokohama-shi, Japan
Kyung Hee University Hospital
๐ฐ๐ทSeoul, Korea, Republic of
The Jikei University Hospital
๐ฏ๐ตMinato-Ku, Japan
Clinical Research Center Spolka z ograniczna odpowiedzialnoscia Medic-R Sp. k.
๐ต๐ฑPoznan, Poland
MedLife, Gastroenterologie
๐ท๐ดBucuresti, Romania
Uniwersytecki Szpital Kliniczny w Bialymstoku, Klinika Gastroenterologii i Chorob Wewnetrznych
๐ต๐ฑBialystok, Poland
Gabinet Lekarski Janusz Rudzinski
๐ต๐ฑBydgoszcz, Poland
Santa Familia, Centrum Badan, Profilaktyki i Leczenia
๐ต๐ฑLodz, Poland
Danderyd University Hospital Corp
๐ธ๐ชStockholm, Sweden
Peermed Clinical Trial Centre
๐ฟ๐ฆJohannesburg, South Africa
Pusan National University Hospital
๐ฐ๐ทBusan, Korea, Republic of
Christchurch Hospital
๐ณ๐ฟChristchurch, New Zealand
State Budgetary Institution of Health of Novosibirsk Region "City Clinical Hospital #12"
๐ท๐บNovosibirsk, Russian Federation
Division of Gastroenterology, Department of Medicine, Samsung Medical Center
๐ฐ๐ทSeoul, Korea, Republic of
Auckland City Hospital
๐ณ๐ฟGrafton, New Zealand
National Taiwan University Hospital
๐จ๐ณTaipei, Taiwan
NZOZ INTER-MED, Centrum Endoskopowe
๐ต๐ฑCzestochowa, Poland
Gabinet Endoskopii Przewodu Pokarmowego
๐ต๐ฑKrakow, Poland
Endoskopia Sp. z o.o.
๐ต๐ฑSopot, Poland
Bay of Plenty District Health Board - Tauranga Hospital
๐ณ๐ฟTauranga, New Zealand
State Budgetary Healthcare Institution "Chelyabinski Regional Clinical Hospital"
๐ท๐บChelyabinsk, Russian Federation
Federal State Budgetary Institution of Science Federal Research Center of Nutrition, Biotechnology and Food Safety
๐ท๐บMoscow, Russian Federation
Wellington Hospital
๐ณ๐ฟNewtown, New Zealand
Spitalul Clinic Colentina - Sectia de Spitulal Clinic Colentina, Gastroenterologie
๐ท๐ดBucuresti, Romania
Zvezdara University Medical Center
๐ท๐ธBelgrade, Serbia
Universitรคtsspital Zรผrich
๐จ๐ญZurich, Switzerland
State Budgetary Healthcare Institution of Nizhny Novgorod Region "Nizhny Novgorod Regional Clinical Hospital n.a. N.A.
๐ท๐บNizhniy Novgorod, Russian Federation
Hospital Universitario Virgen del Rocรญo
๐ช๐ธSevilla, Spain
Hospital Universitario Central de Asturias
๐ช๐ธOviedo, Spain
Hospital da Senhora da Oliveira Guimaraes, E.P.E.
๐ต๐นGuimaraes, Portugal
Centro Hospitalar de Sao Joao, EPE
๐ต๐นPorto, Portugal
Cabinet Particular Policlinic Algomed SRL
๐ท๐ดTimisoara, Romania
Changhua Christian Hospital
๐จ๐ณChanghua, Taiwan
Municipal Health Care Institution "Kharkiv City Clinical Hospital #2 named after prof. O. O. Shalimov", Proctology Department
๐บ๐ฆKharkiv, Ukraine
L.T. Mala State Institution "National Institute of Therapy of National Academy of Medical Sciences of Ukraine"
๐บ๐ฆKharkiv, Ukraine
Hospital Clinico San Carlos
๐ช๐ธMadrid, Spain
State Budgetary Institution of Health Irkustsk Order "Badge of Honor" Regional Clinical Hospital
๐ท๐บIrkutsk, Russian Federation
Hospital Universitario de Fuenlabrada
๐ช๐ธMadrid, Spain
Dr MJ Prins
๐ฟ๐ฆCape Town, South Africa
State Budgetary Healthcare Institution of Moscow "City Clinical Hospital # 24 of Healthcare Department of Moscow"
๐ท๐บMoscow, Russian Federation
Singapore General Hospital
๐ธ๐ฌSingapore, Singapore
Municipal Institution "Cherkasy Regional Hospital of Cherkasy Regional Council", Gastroenterology Department
๐บ๐ฆCherkasy, Ukraine
Kyiv City Clinical Hospital No. 18, Proctology Department
๐บ๐ฆKyiv, Ukraine
Centro Medico Teknon
๐ช๐ธBarcelona, Spain
"Riat" LLC
๐ท๐บSaint Petersburg, Russian Federation
State Budgetary Healthcare Institution of Moscow Region "Moscow Regional Clinical Research Institute n.a. M.F. Vladimirskiy"
๐ท๐บMoscow, Russian Federation
State Institution "Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine"
๐บ๐ฆDnipropetrovsk, Ukraine
Ternopil University Hospital, Regional Center of Gastroenterology with Hepatology
๐บ๐ฆTernopil, Ukraine
Municipal Institution "Zaporizhzhya Regional Clinical Hospital" of Zaporizhzhya Regional Council
๐บ๐ฆZaporizhzhya, Ukraine
Cambridge University Hospital NHS Foundation Trust
๐ฌ๐งCambridge, United Kingdom
Municipal Institution "Odesa Regional Clinical Hospital", Regional Gastroenterology Center based on Surgery Department
๐บ๐ฆOdessa, Ukraine
M.I. Pyrogov Vinnytsia Regional Clinical Hospital, Gastroenterology Department
๐บ๐ฆVinnytsia, Ukraine
Glasgow Clinical Research Facility - Queen Elizabeth University Hospital
๐ฌ๐งGlasgow, United Kingdom
NHS Lothian
๐ฌ๐งEdinburgh, United Kingdom
Vinnytsia Regional Clinical Hospital of War Veterans, Therapy Department #1
๐บ๐ฆVinnytsia, Ukraine
NHS Greater Glasgow and Clyde
๐ฌ๐งGlasgow, United Kingdom
Royal Derby Hospital
๐ฌ๐งDerby, United Kingdom
Imperial College Healthcare NHS Trust, St Mary's Hospital
๐ฌ๐งLondon, United Kingdom
The Pennine Acute Hospitals NHS Trust
๐ฌ๐งBury, United Kingdom
Universitair Ziekenhuis Leuven
๐ง๐ชLeuven, Belgium
Universitatsklinik Innsbruck
๐ฆ๐นInnsbruck, Austria
Kaizen Hospital
๐ฎ๐ณAhmedabad, India
Gleneagles Global Hospitals
๐ฎ๐ณHyderabad, India
Mayo Clinic Arizona
๐บ๐ธScottsdale, Arizona, United States
SR Kalla Memorial Gastro and General Hospital
๐ฎ๐ณJaipur, India
Unimed Ajara LLC - Batumi Referral Hospital
๐ฌ๐ชBatumi, Georgia
M S Ramaiah Medical College and Hospital
๐ฎ๐ณBangalore, India
Apollo Speciality Hospital
๐ฎ๐ณChennai, India
Lokmanya Tilak Municipal General Hospital
๐ฎ๐ณMumbai, India
Surat Institute of Digestive Sciences
๐ฎ๐ณSurat, India
Kasturba Hospital Medical College
๐ฎ๐ณUdupi, India
Dayanand Medical College & Hospital
๐ฎ๐ณLudhiana, India
Samvedna Hospital
๐ฎ๐ณVaranasi, India
Gandhi Hospital
๐ฎ๐ณSecunderabad, India
Cabinet Medical Individual Dr Tirnaveanue Amelita, Gastroenterologie
๐ท๐ดOradea, Romania
Beaumont Hospital
๐ฎ๐ชDublin, Ireland
Norfolk and Norwich University Hospital NHS Foundation Trust
๐ฌ๐งNorwich, Norfolk, United Kingdom
KM Management, s.r.o., Gastroenterologicke a hepatologicke centrum Nitra
๐ธ๐ฐNitra, Slovakia
Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou Branch
๐จ๐ณTaoyuan, Taiwan
Mackay Memorial Hospital, Taipei
๐จ๐ณTaipei, Taiwan
Akademiska Sjukhuset
๐ธ๐ชUppsala, Sweden
UOC Gastroenterologia
๐ฎ๐นPadova, Italy
Azienda Ospedaliero-Universitaria Pisana - Presidio Ospedaliero Cisanello
๐ฎ๐นPisa, Italy
Wycombe Hospital
๐ฌ๐งHigh Wycombe, United Kingdom
Biomedical Research Unit
๐ฌ๐งNottingham, United Kingdom
Oxford University Hospitals NHS Trust
๐ฌ๐งOxford, United Kingdom
St Helens and Knowsley Teaching Hospitals NHS Trust
๐ฌ๐งPrescot, United Kingdom
Southampton National Institute for Health Research, Wellcome Trust Clinical Research Facility
๐ฌ๐งSouthampton, United Kingdom
Saga-Ken Medical Centre Koseikan
๐ฏ๐ตSaga-shi, Japan
Kitasato University Hospital,THE KITASATO INSTITUTE
๐ฏ๐ตSagamihara, Japan
Saga University Hospital
๐ฏ๐ตSaga, Japan
Saint Petersburg State Budgetary Healthcare Institution "City Polyclinic #38"
๐ท๐บSaint-Petersburg, Russian Federation
"Scientific Research Centre ECO-safety" LLC
๐ท๐บSaint-Petersburg, Russian Federation
Treatment and Prevention Interdistrict Institution "Smolenskie kliniki" LLC
๐ท๐บSmolensk, Russian Federation
Tyumen Regional State Autonomous Healthcare Institution << Consulting and Diagnostic Centre <<Endos>>
๐ท๐บTyumen, Russian Federation
The Queen Elizabeth Hospital
๐ฆ๐บWoodville South, South Australia, Australia
Cabrini Hospital
๐ฆ๐บMalvern, Victoria, Australia
Footscray Hospital
๐ฆ๐บFootscray, Victoria, Australia
TDDC San Marcos
๐บ๐ธSan Marcos, Texas, United States
State Budgetary Healthcare Institution of the Novosibirsk Region "State Novosibirsk Regional Clinical Hospital"
๐ท๐บNovosibirsk, Russian Federation
State Healthcare Institution "Regional Clinical Hospital"
๐ท๐บSaratov, Russian Federation
Louisiana Research Center, LLC
๐บ๐ธShreveport, Louisiana, United States
MGG Group Co., Inc., Chevy Chase Clinical Research
๐บ๐ธChevy Chase, Maryland, United States
Gastro Center of Maryland
๐บ๐ธColumbia, Maryland, United States
Clinical Research Institute of Michigan, LLC
๐บ๐ธChesterfield, Michigan, United States
Washington University School of Medicine
๐บ๐ธSaint Louis, Missouri, United States
Fargo Gastroenterology and Hepatology Clinic
๐บ๐ธFargo, North Dakota, United States
Carolina's GI Research LLC
๐บ๐ธRaleigh, North Carolina, United States
Great Lakes Gastroenterology Research, LLC
๐บ๐ธMentor, Ohio, United States
Gastroenterology Associates of Orangeburg
๐บ๐ธOrangeburg, South Carolina, United States
University of Wisconsin Hospital & Clinics
๐บ๐ธMadison, Wisconsin, United States
Instituto de Investigaciones Clinicas Mar del Plata
๐ฆ๐ทMar del Plata, Argentina
Coastal Digestive Health
๐ฆ๐บMountain Creek, Queensland, Australia
St. Vincent's Hospital Sydney
๐ฆ๐บDarlinghurst, New South Wales, Australia
Alfred Hospital
๐ฆ๐บMelbourne, Victoria, Australia
GZA Ziekenhuizen, campus Sint-Vincentius
๐ง๐ชAntwerpen, Belgium
Toronto Digestive Disease Associates Inc.
๐จ๐ฆVaughan, Ontario, Canada
Clinical Hospital Dubrava
๐ญ๐ทZagreb, Croatia
ISCARE a.s. (Klinicke centrum ISCARE), Klinicke a vyzkumne centrum pro strevni zanety
๐จ๐ฟPraha 9, Czechia
APHP - Hopital Beaujon - Clichy - Universite Paris VII
๐ซ๐ทClichy, France
CHU Grenoble Alpes
๐ซ๐ทLa Tronche, France
Hopital Nord
๐ซ๐ทMarseille, France
CHU de Montpellier-Hopital Saint Eloi
๐ซ๐ทMontpellier, France
CHU de Bordeaux - Hopital Haut Leveque
๐ซ๐ทPessac, France
Hopital de l'Archet 2
๐ซ๐ทNice, France
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou
๐ซ๐ทRennes Cedex 9, France
Centre Hospitalier Universitaire de Lyon Sud
๐ซ๐ทPierre-Benite, France
CHU de Nancy - Hopital Brabois Adultes
๐ซ๐ทVandoeuvre Les Nancy, France
CHU de Saint Etienne - Hopital Nord
๐ซ๐ทSaint Priest en Jarez, France
Charite Universitaetsmedizin Berlin
๐ฉ๐ชBerlin, Germany
Charite - Universitatsmedizin Berlin
๐ฉ๐ชBerlin, Germany
Universitatsklinikum Schleswig-Holstein
๐ฉ๐ชKiel, Schleswig Holstein, Germany
Stadtisches Klinikum Braunschweig gGmbH
๐ฉ๐ชBraunschweig, Germany
DRK Kliniken Berlin - Westend - Klinik fuer Innere Medizin
๐ฉ๐ชBerlin, Germany
Universitatsklinikum Freiburg
๐ฉ๐ชFreiburg, Germany
Gastroenterologische Gemeinschaftspraxis Herne
๐ฉ๐ชHerne, Germany
Medizinische Hochschule Hannover
๐ฉ๐ชHannover, Germany
Agaplesion Markus Krankenhaus
๐ฉ๐ชFrankfurt am Main, Germany
Asklepios Westklinikum Hamburg
๐ฉ๐ชHamburg, Germany
Universitaetsklinik Koln
๐ฉ๐ชKoln, Germany
Klinikum Luneburg
๐ฉ๐ชLรผneburg, Germany
Universitatsklinikum Jena
๐ฉ๐ชJena, Germany
Gastroenterologische Gemeinschaftspraxis Minden
๐ฉ๐ชMinden, Germany
Universitaetsklinikum Tuebingen
๐ฉ๐ชTuebingen, Germany
Klinikum der Universitat Munchen - Grosshadern
๐ฉ๐ชMuenchen, Germany
Universitatsklinikum Ulm, Zentrum Fur Innere Medizin
๐ฉ๐ชUlm, Germany
General Hospital of Athens "Hippokratio", 2nd Internal Medicine Clinic of Athens University, Hepato-gastroenterology Unit
๐ฌ๐ทAthens, Greece
Princess Margaret Hospital
๐ญ๐ฐHong Kong, Hong Kong
Bekes Megyei Kosponti Korhaz, Dr. Rethy Pal Tagkorhaz, IV. Belgyogyaszat - 2. Gasztroenterologia
๐ญ๐บBekescsaba, Hungary
Szent Janos Korhaz es Eszak-budai Egitett Korhazak, I. Belgyogyaszati - Gasztroenterologiai Osztaly
๐ญ๐บBudapest, Hungary
Bugat Pal Korhaz, Belgyogyaszat
๐ญ๐บGyรถngyรถs, Hungary
Karolina Korhaz es Rendelointezet, Altalanos Belgyogyaszat-Gasztroenterologia
๐ญ๐บMosonmagyarovar, Hungary
Debreceni Egyetem Klinikai Kozpont, II. sz. Belgyogyaszati Klinika, Gasztroenterologia
๐ญ๐บDebrecen, Hungary
Citizens Specialty Hospital
๐ฎ๐ณHyderabad, India
S.M.S Medical College & Hospitals
๐ฎ๐ณJaipur, India
Grant Medical Foundation Ruby Hall Clinic
๐ฎ๐ณPune, India
Midas Multispeciality Hospital Pvt. Ltd
๐ฎ๐ณNagpur, India
Suretech Hospital & Research Centre Ltd
๐ฎ๐ณNagpur, India
Shree Giriraj Multispeciality Hospital
๐ฎ๐ณRajkot, India
Rambam Medical Health Care Campus
๐ฎ๐ฑHaifa, Israel
Sterling Hospital
๐ฎ๐ณVadodara, India
UOC Gastroenterologia II
๐ฎ๐นCastellana Grotte, Italy
Rabin Medical Center
๐ฎ๐ฑPetah Tikva, Israel
Hadassah Medical Center
๐ฎ๐ฑJerusalem, Israel
U.O. Fisiopatologia Digestiva
๐ฎ๐นCatanzaro, Italy
Ospedale Clinicizzato SS. Annunziata - Dipartimento di Medicina
๐ฎ๐นChieti, Italy
UOC Gastroenterologia ed Endoscopia Digestiva
๐ฎ๐นRoma, Italy
Osaka University Hospital
๐ฏ๐ตSuita, Osaka, Japan
Nagasaki University Hospital
๐ฏ๐ตNagasaki-shi, Nagasaki, Japan
Istituto Clinico Humanitas
๐ฎ๐นRozzano, Italy
Medical Hospital, Tokyo Medical and Dental University
๐ฏ๐ตBunkyo-ku, Japan
Fukuoka University Chikushi Hospital
๐ฏ๐ตChikushino-shi, Japan
Japanese Red Cross Fukuoka Hospital
๐ฏ๐ตFukuoka-shi, Japan
Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital
๐ฏ๐ตChuo-ku, Japan
Hiroshima University Hospital
๐ฏ๐ตHiroshima, Japan
Kitakyushu City Hospital Organization Kitakyushu Municipal Medical Center
๐ฏ๐ตKitakyushu-shi, Japan
Fukuoka University Hospital
๐ฏ๐ตJonan-ku, Japan
Yamanashi Prefectural Central Hospital
๐ฏ๐ตKofu-shi, Japan
University Hospital, Kyoto Prefectural University of Medicine
๐ฏ๐ตKyoto-shi, Japan
Kurume University Hospital
๐ฏ๐ตKurume-shi, Japan
Hidaka Coloproctology Clinic
๐ฏ๐ตKurume-shi, Japan
Aichi Medical University Hospital
๐ฏ๐ตNagakute-shi, Japan
Kitasato University Kitasato Institute Hospital
๐ฏ๐ตMinato-ku, Japan
Saiseikai Niigata Daini Hospital
๐ฏ๐ตNishi-ku, Japan
Iwate Medical University Hospital
๐ฏ๐ตMorioka-shi, Japan
Hyogo College of Medicine College Hospital
๐ฏ๐ตNishinomiya, Japan
Ishida IBD Clinic
๐ฏ๐ตOita-shi, Japan
Kyorin University Hospital
๐ฏ๐ตMitaka-shi, Japan
Okayama University Hospital
๐ฏ๐ตOkayama-city, Japan
Kinshukai Infusion Clinic
๐ฏ๐ตOsaka, Japan
Osaka City University Hospital
๐ฏ๐ตOsaka, Japan
Tokito Clinic
๐ฏ๐ตSaitama, Japan
Shiga University of Medical Science Hospital
๐ฏ๐ตOtsu, Japan
Wakakusa-Daiichi Hospital
๐ฏ๐ตOsaka, Japan
Toho University Sakura Medical Center
๐ฏ๐ตSakura, Japan
Sapporo Higashi Tokushukai Hospital
๐ฏ๐ตSapporo-shi, Japan
National Hospital Organization Sendai Medical Center
๐ฏ๐ตSendai, Japan
Tokyo Yamate Medical Center
๐ฏ๐ตShinjuku-ku, Japan
Kagawa Prefectural Central Hospital
๐ฏ๐ตTakamatsu-shi, Japan
National Hospital Organization Takasaki General Medical Center
๐ฏ๐ตTakasaki-shi, Japan
Osaka Medical College Hospital
๐ฏ๐ตTakatsuki, Japan
GASTROMED Kopon, Zmudzinski i Wspolnicy Sp. j. Specjalistyczne Centrum Gastrologii i Endoskopii
๐ต๐ฑTorun, Poland
H-T.Centrum Medyczne Spolka z Ograniczona Odpowiedzialnoscia Sp.K.
๐ต๐ฑTychy, Poland
Centrum Zdrowia MDM
๐ต๐ฑWarszawa, Poland
Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych i Administacji w Warszawie
๐ต๐ฑWarszawa, Poland
Municipal City Clinical Hospital of the Emergency Medical Care, 1 st Therapy Department. Danylo Halytsky Lviv National Medical
๐บ๐ฆChernivtsi, Ukraine
Regional Municipal Institution "Chernivtsi Regional Clinical Hospital", Surgical Department
๐บ๐ฆChernivtsi, Ukraine
Medical Center LLC "Health Clinic"
๐บ๐ฆVinnytsia, Ukraine
UF Clinical Research Center
๐บ๐ธGainesville, Florida, United States
Tampa General Hospital
๐บ๐ธTampa, Florida, United States
University of Louisville, Clinical Trials Unit
๐บ๐ธLouisville, Kentucky, United States
Mayo Clinic
๐บ๐ธRochester, Minnesota, United States
Kansas City Research Institute
๐บ๐ธKansas City, Missouri, United States
Consultants for Clinical Research
๐บ๐ธCincinnati, Ohio, United States
UC Health Physicians Clifton
๐บ๐ธCincinnati, Ohio, United States
Quality Medical Research
๐บ๐ธNashville, Tennessee, United States
Vanderbilt University Medical Center - IBD Clinic
๐บ๐ธNashville, Tennessee, United States
Gastroenterology Research of San Antonio
๐บ๐ธSan Antonio, Texas, United States
Clinical Associates in Research Therapeutics of America, LLC
๐บ๐ธSan Antonio, Texas, United States
McGuire DVAMC
๐บ๐ธRichmond, Virginia, United States
Royal University Hospital
๐จ๐ฆSaskatoon, Saskatchewan, Canada
University Medical Center Utrecht
๐ณ๐ฑUtrecht, Netherlands
Queen Mary Hospital
๐ญ๐ฐHong Kong, Hong Kong