MedPath

Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis

Phase 3
Active, not recruiting
Conditions
Ulcerative Colitis
Interventions
Drug: Filgotinib
Drug: Placebo
Registration Number
NCT02914535
Lead Sponsor
Galapagos NV
Brief Summary

The primary objective of this study is to observe the long-term safety of filgotinib in adults who have completed or met protocol specified efficacy discontinuation criteria in a prior filgotinib treatment study in ulcerative colitis (UC).

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
1173
Inclusion Criteria
  • Must have the ability to understand and sign a written informed consent form (ICF), which must be obtained prior to initiation of study procedures associated with this trial
  • Must have enrolled in Gilead-sponsored UC parent protocol GS US 418-3898 or any other Gilead/Galapagos-sponsored filgotinib treatment study for UC
  • Must have completed all required procedures or met protocol-specified efficacy discontinuation criteria in a prior filgotinib treatment study for UC
  • Females of childbearing potential must have a negative pregnancy test at Day 1
  • Female individuals of childbearing potential who engage in heterosexual intercourse must agree to use protocol specified method(s) of contraception for the duration described
  • Willingness to refrain from live or attenuated vaccines during the study and for 12 weeks after last dose of study drug

Key

Read More
Exclusion Criteria
  • Known hypersensitivity to the study drug
  • Any chronic medical condition (including, but not limited to, cardiac or pulmonary disease, alcohol or drug abuse) that, in the opinion of the Investigator or sponsor, would make the subject unsuitable for the study or would prevent compliance with the study protocol
  • Females of reproductive potential who are unwilling to abide by protocol-specified contraceptive methods as defined
  • Use of prohibited medications as outlined in the protocol

NOTE: Other protocol defined Inclusion/ Exclusion criteria may apply.

Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Filgotinib 100 mg (blinded dosing)FilgotinibFilgotinib 100 mg + placebo to match filgotinib 200 mg for up to 336 weeks
Filgotinib 200 mg (blinded dosing)PlaceboFilgotinib 200 mg + placebo to match filgotinib 100 mg for up to 336 weeks
Filgotinib 100 mg (blinded dosing)PlaceboFilgotinib 100 mg + placebo to match filgotinib 200 mg for up to 336 weeks
Placebo (blinded dosing)PlaceboPlacebo to match filgotinib 200 mg + placebo to match filgotinib 100 mg for up to 336 weeks
Filgotinib 200 mg (open-label)FilgotinibFilgotinib 200 mg for up to 336 weeks
Filgotinib 200 mg (blinded dosing)FilgotinibFilgotinib 200 mg + placebo to match filgotinib 100 mg for up to 336 weeks
Filgotinib 100 mg (open-label)FilgotinibFilgotinib 100 mg for up to 336 weeks
Primary Outcome Measures
NameTimeMethod
Overall Safety Profile of Filgotinib Evaluated by Proportion of Participants Experiencing Adverse Events and Abnormal Clinical Laboratory TestsUp to 336 weeks plus 30 days
Secondary Outcome Measures
NameTimeMethod
Change From Baseline in Components of Mayo Clinic Score (MCS)Baseline and up to 336 weeks

Trial Locations

Locations (323)

Cedars Sinai Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Los Angeles, California, United States

University of Miami Crohn's and Colitis Center

๐Ÿ‡บ๐Ÿ‡ธ

Miami, Florida, United States

Cordova Research Institute

๐Ÿ‡บ๐Ÿ‡ธ

Miami, Florida, United States

Massachusetts General Hospital - Crohn's and Colitis Center

๐Ÿ‡บ๐Ÿ‡ธ

Boston, Massachusetts, United States

Meritus Center for Clinical Research

๐Ÿ‡บ๐Ÿ‡ธ

Hagerstown, Maryland, United States

Bodyclinic

๐Ÿ‡ต๐Ÿ‡ฑ

Warszawa, Poland

Centrum Medyczne Oporow

๐Ÿ‡ต๐Ÿ‡ฑ

Wroclaw, Poland

Twoja Przychodnia-Szczecinskie Centrum Medyczne

๐Ÿ‡ต๐Ÿ‡ฑ

Szczecin, Poland

Municipal Non-profit Enterprise "Consultative and Diagnostic Center" of Pechersk District of Kyiv, Therapy Department

๐Ÿ‡บ๐Ÿ‡ฆ

Kyiv, Ukraine

Niepubliczny Zaklad Opieki Zrodotnej VIVAMED Jadwige Miecz

๐Ÿ‡ต๐Ÿ‡ฑ

Warszawa, Poland

Gelre Hospital

๐Ÿ‡ณ๐Ÿ‡ฑ

Apeldoorn, Netherlands

Krakowskie Centrum Medyczne Sp. z o.o

๐Ÿ‡ต๐Ÿ‡ฑ

Krakรณw, Poland

EUGASTRO GmbH

๐Ÿ‡ฉ๐Ÿ‡ช

Leipzig, Germany

Delta Research Partners, LLC

๐Ÿ‡บ๐Ÿ‡ธ

Monroe, Louisiana, United States

Gastro One

๐Ÿ‡บ๐Ÿ‡ธ

Germantown, Tennessee, United States

Atlanta Gastroenterology Specialist, PC

๐Ÿ‡บ๐Ÿ‡ธ

Suwanee, Georgia, United States

Gastroenterology Associates Of Central Georgia, LLC

๐Ÿ‡บ๐Ÿ‡ธ

Macon, Georgia, United States

Florida Medical Clinic, P.A

๐Ÿ‡บ๐Ÿ‡ธ

Zephyrhills, Florida, United States

South Denver Gastroenterology, PC

๐Ÿ‡บ๐Ÿ‡ธ

Lone Tree, Colorado, United States

Investigative Clinical Research

๐Ÿ‡บ๐Ÿ‡ธ

Annapolis, Maryland, United States

Center for Digestive Health Research

๐Ÿ‡บ๐Ÿ‡ธ

Troy, Michigan, United States

NY Scientific

๐Ÿ‡บ๐Ÿ‡ธ

Brooklyn, New York, United States

NYU Langone Long Island Clinical Research Associates

๐Ÿ‡บ๐Ÿ‡ธ

Great Neck, New York, United States

San Antonio Military Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Fort Sam Houston, Texas, United States

Digestive Health Specialists Of The Southeast

๐Ÿ‡บ๐Ÿ‡ธ

Dothan, Alabama, United States

Florida Research Institute

๐Ÿ‡บ๐Ÿ‡ธ

Lakewood Ranch, Florida, United States

VA Long Beach Healthcare System

๐Ÿ‡บ๐Ÿ‡ธ

Long Beach, California, United States

Gastrointestinal Specialists of Georgia

๐Ÿ‡บ๐Ÿ‡ธ

Marietta, Georgia, United States

Connecticut GI PC-Research Division

๐Ÿ‡บ๐Ÿ‡ธ

Farmington, Connecticut, United States

University of Iowa Hospitals and Clinics

๐Ÿ‡บ๐Ÿ‡ธ

Iowa City, Iowa, United States

Gastroenterology Group of Naples

๐Ÿ‡บ๐Ÿ‡ธ

Naples, Florida, United States

Advanced Medical Research Center

๐Ÿ‡บ๐Ÿ‡ธ

Port Orange, Florida, United States

The University of Texas Health Science Center at Houston

๐Ÿ‡บ๐Ÿ‡ธ

Houston, Texas, United States

University Hospital Center Zagreb

๐Ÿ‡ญ๐Ÿ‡ท

Zagreb, Croatia

Rapid City Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Rapid City, South Dakota, United States

Princess Alexandra Hospital

๐Ÿ‡ฆ๐Ÿ‡บ

Woolloongabba, Queensland, Australia

MHAT "Sveta Petka" AD

๐Ÿ‡ง๐Ÿ‡ฌ

Vidin, Bulgaria

MHAT Sveti Pantaleymon- Pleven OOD

๐Ÿ‡ง๐Ÿ‡ฌ

Pleven, Bulgaria

The Gordon and Leslie Diamond Health Care Centre

๐Ÿ‡จ๐Ÿ‡ฆ

Vancouver, British Columbia, Canada

AKH-Medizinische Universitat Wien

๐Ÿ‡ฆ๐Ÿ‡น

Wien, Austria

DHAT Research Institute

๐Ÿ‡บ๐Ÿ‡ธ

Garland, Texas, United States

Mater Misericordiae Ltd

๐Ÿ‡ฆ๐Ÿ‡บ

South Brisbane, Queensland, Australia

Monash Medical Centre

๐Ÿ‡ฆ๐Ÿ‡บ

Clayton, New South Wales, Australia

University of Calgary, Heritage Medical Research Clinic

๐Ÿ‡จ๐Ÿ‡ฆ

Calgary, Alberta, Canada

Texas Digestive Disease Consultants

๐Ÿ‡บ๐Ÿ‡ธ

Southlake, Texas, United States

Allegiance Research Specialists, LLC

๐Ÿ‡บ๐Ÿ‡ธ

Wauwatosa, Wisconsin, United States

"MDHAT Dr. St.Cherkezov" AD

๐Ÿ‡ง๐Ÿ‡ฌ

Veliko Tarnovo, Bulgaria

Spring Gastroenterology

๐Ÿ‡บ๐Ÿ‡ธ

The Woodlands, Texas, United States

Nepean Hospital

๐Ÿ‡ฆ๐Ÿ‡บ

Kingswood, New South Wales, Australia

Instituto Mรฉdico Cer

๐Ÿ‡ฆ๐Ÿ‡ท

Quilmes, Argentina

Baylor College of Medicine - Baylor Medical Center

๐Ÿ‡บ๐Ÿ‡ธ

Houston, Texas, United States

University of Virginia Health System

๐Ÿ‡บ๐Ÿ‡ธ

Charlottesville, Virginia, United States

Gastroenterology Associates of Tidewater

๐Ÿ‡บ๐Ÿ‡ธ

Chesapeake, Virginia, United States

G.E.P. Clinic, s r.o.

๐Ÿ‡จ๐Ÿ‡ฟ

Praha 3, Czechia

Medi Club Georgia LLC

๐Ÿ‡ฌ๐Ÿ‡ช

Tbilisi, Georgia

CUB Hopital Erasme

๐Ÿ‡ง๐Ÿ‡ช

Brussel, Belgium

Centre Hospitalier Chretien (CHC) - Clinique Saint-Joseph

๐Ÿ‡ง๐Ÿ‡ช

Liรจge, Belgium

CHU Amiens Picardie

๐Ÿ‡ซ๐Ÿ‡ท

Amiens Cedex 1, France

CHU Hotel-Dieu

๐Ÿ‡ซ๐Ÿ‡ท

Nantes, France

CHU de Caen

๐Ÿ‡ซ๐Ÿ‡ท

Caen Cedex 9, France

Hamilton Health Sciences Corporation, McMaster University Medical Centre

๐Ÿ‡จ๐Ÿ‡ฆ

Hamilton, Ontario, Canada

CHU de Clermont-Ferrand - Hopital d'Estaing

๐Ÿ‡ซ๐Ÿ‡ท

Clermont-Ferrand, France

CHU de Dijon Bourgogne - Hopital Francois Mitterand

๐Ÿ‡ซ๐Ÿ‡ท

Dijon, France

Hopital Universitaire de Bicetre

๐Ÿ‡ซ๐Ÿ‡ท

Le Kremlin Bicetre, France

Hepato-Gastroenterology HK, s.r.o.

๐Ÿ‡จ๐Ÿ‡ฟ

Hradec Kralove, Czechia

Oblastni nemocnice Mlada Boleslav, a.s., nemocnice Stredoceskeho kraje, Gastroenterologicke oddeleni

๐Ÿ‡จ๐Ÿ‡ฟ

Mlada Boleslav, Czechia

Centre Hospitalier Regional Universitaire de Lille

๐Ÿ‡ซ๐Ÿ‡ท

Lille, France

CHU de Toulouse - Hopital Rangueil

๐Ÿ‡ซ๐Ÿ‡ท

Toulouse, France

VGM Hospital Institute of Gastroenterology

๐Ÿ‡ฎ๐Ÿ‡ณ

Coimbatore, India

Centre for Liver Research & Diagnostics

๐Ÿ‡ฎ๐Ÿ‡ณ

Hyderabad, India

Kasturba Medical College (KMC) Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Mangaluru, India

Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Kozponti Felnott Szakrendelo

๐Ÿ‡ญ๐Ÿ‡บ

Budapest, Hungary

Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital

๐Ÿ‡ญ๐Ÿ‡ฐ

Shatin, Hong Kong

The Catholic University of Korea, St. Vincent's Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Suwon-si, Gyeonggi-do, Korea, Republic of

Hospital Queen Elizabeth

๐Ÿ‡ฒ๐Ÿ‡พ

Kota Kinabalu, Malaysia

Bnai Zion Medical Center

๐Ÿ‡ฎ๐Ÿ‡ฑ

Haifa, Israel

Yonsei University Health System, Severance Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Seoul, Korea, Republic of

Yeungnam University Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Daegu, Korea, Republic of

Shaare Zedek Medical Center

๐Ÿ‡ฎ๐Ÿ‡ฑ

Jerusalem, Israel

Wakayama Medical University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Wakayama-shi, Japan

Yonsei University Wonju Severance Christian Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Wonju, Korea, Republic of

Centrum Opieki Zdrowotnej Orkan-Med Stec-Michalska Sp. J.

๐Ÿ‡ต๐Ÿ‡ฑ

Ksawerรณw, Poland

Academic Medical Center (AMC)

๐Ÿ‡ณ๐Ÿ‡ฑ

Amsterdam, Netherlands

PCR-Phylasis Clinicas Research S. de R.L. de C.V.

๐Ÿ‡ฒ๐Ÿ‡ฝ

Cuautitlรกn Izcalli, Mexico

VITAMED Galaj i Cichomski spรณlka jawna

๐Ÿ‡ต๐Ÿ‡ฑ

Bydgoszcz, Poland

Niepubliczny Zaklad Opieki Zdrowotnej ALL-MEDICUS

๐Ÿ‡ต๐Ÿ‡ฑ

Katowice, Poland

Centrum Innowacyjnych Terapii Sp. z o.o.

๐Ÿ‡ต๐Ÿ‡ฑ

Piaseczno, Poland

Ieda Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Toyota-shi, Japan

Gabinet Lekarski Dr. Hab. N. Med. Bartosz Korczowski

๐Ÿ‡ต๐Ÿ‡ฑ

Rzeszรณw, Poland

Endocsopia Digestiva Centralizzata - ASST Fatebenefratelli Sacco, Ospedale Fatebenefratelli e Oftalmico

๐Ÿ‡ฎ๐Ÿ‡น

Milano, Italy

Kangbuk Samsung Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Seoul, Korea, Republic of

Hospital Pulau Pinang

๐Ÿ‡ฒ๐Ÿ‡พ

George Town, Malaysia

Gastroenterologische Praxis Balsiger, Seibold und Partner

๐Ÿ‡จ๐Ÿ‡ญ

Bern, Switzerland

Ivanto-Frankivsk Central City Clinic Hospital, Therapy Department #1. State Higher Education Institution Ivano-Frankivsk National

๐Ÿ‡บ๐Ÿ‡ฆ

Ivano-Frankivsk, Ukraine

Municipal Institution of Health Care "Regional Hospital of War Veterans", Therapeutic Department No1

๐Ÿ‡บ๐Ÿ‡ฆ

Kharkiv, Ukraine

Odesa Clinical Railway Hospital Branch of "Healthcare Center" of Public joint stock company "Ukrainian Railway"

๐Ÿ‡บ๐Ÿ‡ฆ

Odessa, Ukraine

Skane University Hospital

๐Ÿ‡ธ๐Ÿ‡ช

Malmo, Sweden

Asan Medical Center

๐Ÿ‡ฐ๐Ÿ‡ท

Seoul, Korea, Republic of

Ofuna Chuo Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Kamakura, Japan

Tokai University Hachioji Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Hachioji, Japan

Colo-proctology Center Matsushima Clinic

๐Ÿ‡ฏ๐Ÿ‡ต

Yokohama-shi, Japan

Kyung Hee University Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Seoul, Korea, Republic of

The Jikei University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Minato-Ku, Japan

Clinical Research Center Spolka z ograniczna odpowiedzialnoscia Medic-R Sp. k.

๐Ÿ‡ต๐Ÿ‡ฑ

Poznan, Poland

MedLife, Gastroenterologie

๐Ÿ‡ท๐Ÿ‡ด

Bucuresti, Romania

Uniwersytecki Szpital Kliniczny w Bialymstoku, Klinika Gastroenterologii i Chorob Wewnetrznych

๐Ÿ‡ต๐Ÿ‡ฑ

Bialystok, Poland

Gabinet Lekarski Janusz Rudzinski

๐Ÿ‡ต๐Ÿ‡ฑ

Bydgoszcz, Poland

Santa Familia, Centrum Badan, Profilaktyki i Leczenia

๐Ÿ‡ต๐Ÿ‡ฑ

Lodz, Poland

Danderyd University Hospital Corp

๐Ÿ‡ธ๐Ÿ‡ช

Stockholm, Sweden

Peermed Clinical Trial Centre

๐Ÿ‡ฟ๐Ÿ‡ฆ

Johannesburg, South Africa

Pusan National University Hospital

๐Ÿ‡ฐ๐Ÿ‡ท

Busan, Korea, Republic of

Christchurch Hospital

๐Ÿ‡ณ๐Ÿ‡ฟ

Christchurch, New Zealand

State Budgetary Institution of Health of Novosibirsk Region "City Clinical Hospital #12"

๐Ÿ‡ท๐Ÿ‡บ

Novosibirsk, Russian Federation

Division of Gastroenterology, Department of Medicine, Samsung Medical Center

๐Ÿ‡ฐ๐Ÿ‡ท

Seoul, Korea, Republic of

Auckland City Hospital

๐Ÿ‡ณ๐Ÿ‡ฟ

Grafton, New Zealand

National Taiwan University Hospital

๐Ÿ‡จ๐Ÿ‡ณ

Taipei, Taiwan

NZOZ INTER-MED, Centrum Endoskopowe

๐Ÿ‡ต๐Ÿ‡ฑ

Czestochowa, Poland

Gabinet Endoskopii Przewodu Pokarmowego

๐Ÿ‡ต๐Ÿ‡ฑ

Krakow, Poland

Endoskopia Sp. z o.o.

๐Ÿ‡ต๐Ÿ‡ฑ

Sopot, Poland

Bay of Plenty District Health Board - Tauranga Hospital

๐Ÿ‡ณ๐Ÿ‡ฟ

Tauranga, New Zealand

State Budgetary Healthcare Institution "Chelyabinski Regional Clinical Hospital"

๐Ÿ‡ท๐Ÿ‡บ

Chelyabinsk, Russian Federation

Federal State Budgetary Institution of Science Federal Research Center of Nutrition, Biotechnology and Food Safety

๐Ÿ‡ท๐Ÿ‡บ

Moscow, Russian Federation

Wellington Hospital

๐Ÿ‡ณ๐Ÿ‡ฟ

Newtown, New Zealand

Spitalul Clinic Colentina - Sectia de Spitulal Clinic Colentina, Gastroenterologie

๐Ÿ‡ท๐Ÿ‡ด

Bucuresti, Romania

Zvezdara University Medical Center

๐Ÿ‡ท๐Ÿ‡ธ

Belgrade, Serbia

Universitรคtsspital Zรผrich

๐Ÿ‡จ๐Ÿ‡ญ

Zurich, Switzerland

State Budgetary Healthcare Institution of Nizhny Novgorod Region "Nizhny Novgorod Regional Clinical Hospital n.a. N.A.

๐Ÿ‡ท๐Ÿ‡บ

Nizhniy Novgorod, Russian Federation

Hospital Universitario Virgen del Rocรญo

๐Ÿ‡ช๐Ÿ‡ธ

Sevilla, Spain

Hospital Universitario Central de Asturias

๐Ÿ‡ช๐Ÿ‡ธ

Oviedo, Spain

Hospital da Senhora da Oliveira Guimaraes, E.P.E.

๐Ÿ‡ต๐Ÿ‡น

Guimaraes, Portugal

Centro Hospitalar de Sao Joao, EPE

๐Ÿ‡ต๐Ÿ‡น

Porto, Portugal

Cabinet Particular Policlinic Algomed SRL

๐Ÿ‡ท๐Ÿ‡ด

Timisoara, Romania

Changhua Christian Hospital

๐Ÿ‡จ๐Ÿ‡ณ

Changhua, Taiwan

Municipal Health Care Institution "Kharkiv City Clinical Hospital #2 named after prof. O. O. Shalimov", Proctology Department

๐Ÿ‡บ๐Ÿ‡ฆ

Kharkiv, Ukraine

L.T. Mala State Institution "National Institute of Therapy of National Academy of Medical Sciences of Ukraine"

๐Ÿ‡บ๐Ÿ‡ฆ

Kharkiv, Ukraine

Hospital Clinico San Carlos

๐Ÿ‡ช๐Ÿ‡ธ

Madrid, Spain

State Budgetary Institution of Health Irkustsk Order "Badge of Honor" Regional Clinical Hospital

๐Ÿ‡ท๐Ÿ‡บ

Irkutsk, Russian Federation

Hospital Universitario de Fuenlabrada

๐Ÿ‡ช๐Ÿ‡ธ

Madrid, Spain

Dr MJ Prins

๐Ÿ‡ฟ๐Ÿ‡ฆ

Cape Town, South Africa

State Budgetary Healthcare Institution of Moscow "City Clinical Hospital # 24 of Healthcare Department of Moscow"

๐Ÿ‡ท๐Ÿ‡บ

Moscow, Russian Federation

Singapore General Hospital

๐Ÿ‡ธ๐Ÿ‡ฌ

Singapore, Singapore

Municipal Institution "Cherkasy Regional Hospital of Cherkasy Regional Council", Gastroenterology Department

๐Ÿ‡บ๐Ÿ‡ฆ

Cherkasy, Ukraine

Kyiv City Clinical Hospital No. 18, Proctology Department

๐Ÿ‡บ๐Ÿ‡ฆ

Kyiv, Ukraine

Centro Medico Teknon

๐Ÿ‡ช๐Ÿ‡ธ

Barcelona, Spain

"Riat" LLC

๐Ÿ‡ท๐Ÿ‡บ

Saint Petersburg, Russian Federation

State Budgetary Healthcare Institution of Moscow Region "Moscow Regional Clinical Research Institute n.a. M.F. Vladimirskiy"

๐Ÿ‡ท๐Ÿ‡บ

Moscow, Russian Federation

State Institution "Institute of Gastroenterology of National Academy of Medical Sciences of Ukraine"

๐Ÿ‡บ๐Ÿ‡ฆ

Dnipropetrovsk, Ukraine

Ternopil University Hospital, Regional Center of Gastroenterology with Hepatology

๐Ÿ‡บ๐Ÿ‡ฆ

Ternopil, Ukraine

Municipal Institution "Zaporizhzhya Regional Clinical Hospital" of Zaporizhzhya Regional Council

๐Ÿ‡บ๐Ÿ‡ฆ

Zaporizhzhya, Ukraine

Cambridge University Hospital NHS Foundation Trust

๐Ÿ‡ฌ๐Ÿ‡ง

Cambridge, United Kingdom

Municipal Institution "Odesa Regional Clinical Hospital", Regional Gastroenterology Center based on Surgery Department

๐Ÿ‡บ๐Ÿ‡ฆ

Odessa, Ukraine

M.I. Pyrogov Vinnytsia Regional Clinical Hospital, Gastroenterology Department

๐Ÿ‡บ๐Ÿ‡ฆ

Vinnytsia, Ukraine

Glasgow Clinical Research Facility - Queen Elizabeth University Hospital

๐Ÿ‡ฌ๐Ÿ‡ง

Glasgow, United Kingdom

NHS Lothian

๐Ÿ‡ฌ๐Ÿ‡ง

Edinburgh, United Kingdom

Vinnytsia Regional Clinical Hospital of War Veterans, Therapy Department #1

๐Ÿ‡บ๐Ÿ‡ฆ

Vinnytsia, Ukraine

NHS Greater Glasgow and Clyde

๐Ÿ‡ฌ๐Ÿ‡ง

Glasgow, United Kingdom

Royal Derby Hospital

๐Ÿ‡ฌ๐Ÿ‡ง

Derby, United Kingdom

Imperial College Healthcare NHS Trust, St Mary's Hospital

๐Ÿ‡ฌ๐Ÿ‡ง

London, United Kingdom

The Pennine Acute Hospitals NHS Trust

๐Ÿ‡ฌ๐Ÿ‡ง

Bury, United Kingdom

Universitair Ziekenhuis Leuven

๐Ÿ‡ง๐Ÿ‡ช

Leuven, Belgium

Universitatsklinik Innsbruck

๐Ÿ‡ฆ๐Ÿ‡น

Innsbruck, Austria

Kaizen Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Ahmedabad, India

Gleneagles Global Hospitals

๐Ÿ‡ฎ๐Ÿ‡ณ

Hyderabad, India

Mayo Clinic Arizona

๐Ÿ‡บ๐Ÿ‡ธ

Scottsdale, Arizona, United States

SR Kalla Memorial Gastro and General Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Jaipur, India

Unimed Ajara LLC - Batumi Referral Hospital

๐Ÿ‡ฌ๐Ÿ‡ช

Batumi, Georgia

M S Ramaiah Medical College and Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Bangalore, India

Apollo Speciality Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Chennai, India

Lokmanya Tilak Municipal General Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Mumbai, India

Surat Institute of Digestive Sciences

๐Ÿ‡ฎ๐Ÿ‡ณ

Surat, India

Kasturba Hospital Medical College

๐Ÿ‡ฎ๐Ÿ‡ณ

Udupi, India

Dayanand Medical College & Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Ludhiana, India

Samvedna Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Varanasi, India

Gandhi Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Secunderabad, India

Cabinet Medical Individual Dr Tirnaveanue Amelita, Gastroenterologie

๐Ÿ‡ท๐Ÿ‡ด

Oradea, Romania

Beaumont Hospital

๐Ÿ‡ฎ๐Ÿ‡ช

Dublin, Ireland

Norfolk and Norwich University Hospital NHS Foundation Trust

๐Ÿ‡ฌ๐Ÿ‡ง

Norwich, Norfolk, United Kingdom

KM Management, s.r.o., Gastroenterologicke a hepatologicke centrum Nitra

๐Ÿ‡ธ๐Ÿ‡ฐ

Nitra, Slovakia

Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou Branch

๐Ÿ‡จ๐Ÿ‡ณ

Taoyuan, Taiwan

Mackay Memorial Hospital, Taipei

๐Ÿ‡จ๐Ÿ‡ณ

Taipei, Taiwan

Akademiska Sjukhuset

๐Ÿ‡ธ๐Ÿ‡ช

Uppsala, Sweden

UOC Gastroenterologia

๐Ÿ‡ฎ๐Ÿ‡น

Padova, Italy

Azienda Ospedaliero-Universitaria Pisana - Presidio Ospedaliero Cisanello

๐Ÿ‡ฎ๐Ÿ‡น

Pisa, Italy

Wycombe Hospital

๐Ÿ‡ฌ๐Ÿ‡ง

High Wycombe, United Kingdom

Biomedical Research Unit

๐Ÿ‡ฌ๐Ÿ‡ง

Nottingham, United Kingdom

Oxford University Hospitals NHS Trust

๐Ÿ‡ฌ๐Ÿ‡ง

Oxford, United Kingdom

St Helens and Knowsley Teaching Hospitals NHS Trust

๐Ÿ‡ฌ๐Ÿ‡ง

Prescot, United Kingdom

Southampton National Institute for Health Research, Wellcome Trust Clinical Research Facility

๐Ÿ‡ฌ๐Ÿ‡ง

Southampton, United Kingdom

Saga-Ken Medical Centre Koseikan

๐Ÿ‡ฏ๐Ÿ‡ต

Saga-shi, Japan

Kitasato University Hospital,THE KITASATO INSTITUTE

๐Ÿ‡ฏ๐Ÿ‡ต

Sagamihara, Japan

Saga University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Saga, Japan

Saint Petersburg State Budgetary Healthcare Institution "City Polyclinic #38"

๐Ÿ‡ท๐Ÿ‡บ

Saint-Petersburg, Russian Federation

"Scientific Research Centre ECO-safety" LLC

๐Ÿ‡ท๐Ÿ‡บ

Saint-Petersburg, Russian Federation

Treatment and Prevention Interdistrict Institution "Smolenskie kliniki" LLC

๐Ÿ‡ท๐Ÿ‡บ

Smolensk, Russian Federation

Tyumen Regional State Autonomous Healthcare Institution << Consulting and Diagnostic Centre <<Endos>>

๐Ÿ‡ท๐Ÿ‡บ

Tyumen, Russian Federation

The Queen Elizabeth Hospital

๐Ÿ‡ฆ๐Ÿ‡บ

Woodville South, South Australia, Australia

Cabrini Hospital

๐Ÿ‡ฆ๐Ÿ‡บ

Malvern, Victoria, Australia

Footscray Hospital

๐Ÿ‡ฆ๐Ÿ‡บ

Footscray, Victoria, Australia

TDDC San Marcos

๐Ÿ‡บ๐Ÿ‡ธ

San Marcos, Texas, United States

State Budgetary Healthcare Institution of the Novosibirsk Region "State Novosibirsk Regional Clinical Hospital"

๐Ÿ‡ท๐Ÿ‡บ

Novosibirsk, Russian Federation

State Healthcare Institution "Regional Clinical Hospital"

๐Ÿ‡ท๐Ÿ‡บ

Saratov, Russian Federation

Louisiana Research Center, LLC

๐Ÿ‡บ๐Ÿ‡ธ

Shreveport, Louisiana, United States

MGG Group Co., Inc., Chevy Chase Clinical Research

๐Ÿ‡บ๐Ÿ‡ธ

Chevy Chase, Maryland, United States

Gastro Center of Maryland

๐Ÿ‡บ๐Ÿ‡ธ

Columbia, Maryland, United States

Clinical Research Institute of Michigan, LLC

๐Ÿ‡บ๐Ÿ‡ธ

Chesterfield, Michigan, United States

Washington University School of Medicine

๐Ÿ‡บ๐Ÿ‡ธ

Saint Louis, Missouri, United States

Fargo Gastroenterology and Hepatology Clinic

๐Ÿ‡บ๐Ÿ‡ธ

Fargo, North Dakota, United States

Carolina's GI Research LLC

๐Ÿ‡บ๐Ÿ‡ธ

Raleigh, North Carolina, United States

Great Lakes Gastroenterology Research, LLC

๐Ÿ‡บ๐Ÿ‡ธ

Mentor, Ohio, United States

Gastroenterology Associates of Orangeburg

๐Ÿ‡บ๐Ÿ‡ธ

Orangeburg, South Carolina, United States

University of Wisconsin Hospital & Clinics

๐Ÿ‡บ๐Ÿ‡ธ

Madison, Wisconsin, United States

Instituto de Investigaciones Clinicas Mar del Plata

๐Ÿ‡ฆ๐Ÿ‡ท

Mar del Plata, Argentina

Coastal Digestive Health

๐Ÿ‡ฆ๐Ÿ‡บ

Mountain Creek, Queensland, Australia

St. Vincent's Hospital Sydney

๐Ÿ‡ฆ๐Ÿ‡บ

Darlinghurst, New South Wales, Australia

Alfred Hospital

๐Ÿ‡ฆ๐Ÿ‡บ

Melbourne, Victoria, Australia

GZA Ziekenhuizen, campus Sint-Vincentius

๐Ÿ‡ง๐Ÿ‡ช

Antwerpen, Belgium

Toronto Digestive Disease Associates Inc.

๐Ÿ‡จ๐Ÿ‡ฆ

Vaughan, Ontario, Canada

Clinical Hospital Dubrava

๐Ÿ‡ญ๐Ÿ‡ท

Zagreb, Croatia

ISCARE a.s. (Klinicke centrum ISCARE), Klinicke a vyzkumne centrum pro strevni zanety

๐Ÿ‡จ๐Ÿ‡ฟ

Praha 9, Czechia

APHP - Hopital Beaujon - Clichy - Universite Paris VII

๐Ÿ‡ซ๐Ÿ‡ท

Clichy, France

CHU Grenoble Alpes

๐Ÿ‡ซ๐Ÿ‡ท

La Tronche, France

Hopital Nord

๐Ÿ‡ซ๐Ÿ‡ท

Marseille, France

CHU de Montpellier-Hopital Saint Eloi

๐Ÿ‡ซ๐Ÿ‡ท

Montpellier, France

CHU de Bordeaux - Hopital Haut Leveque

๐Ÿ‡ซ๐Ÿ‡ท

Pessac, France

Hopital de l'Archet 2

๐Ÿ‡ซ๐Ÿ‡ท

Nice, France

Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou

๐Ÿ‡ซ๐Ÿ‡ท

Rennes Cedex 9, France

Centre Hospitalier Universitaire de Lyon Sud

๐Ÿ‡ซ๐Ÿ‡ท

Pierre-Benite, France

CHU de Nancy - Hopital Brabois Adultes

๐Ÿ‡ซ๐Ÿ‡ท

Vandoeuvre Les Nancy, France

CHU de Saint Etienne - Hopital Nord

๐Ÿ‡ซ๐Ÿ‡ท

Saint Priest en Jarez, France

Charite Universitaetsmedizin Berlin

๐Ÿ‡ฉ๐Ÿ‡ช

Berlin, Germany

Charite - Universitatsmedizin Berlin

๐Ÿ‡ฉ๐Ÿ‡ช

Berlin, Germany

Universitatsklinikum Schleswig-Holstein

๐Ÿ‡ฉ๐Ÿ‡ช

Kiel, Schleswig Holstein, Germany

Stadtisches Klinikum Braunschweig gGmbH

๐Ÿ‡ฉ๐Ÿ‡ช

Braunschweig, Germany

DRK Kliniken Berlin - Westend - Klinik fuer Innere Medizin

๐Ÿ‡ฉ๐Ÿ‡ช

Berlin, Germany

Universitatsklinikum Freiburg

๐Ÿ‡ฉ๐Ÿ‡ช

Freiburg, Germany

Gastroenterologische Gemeinschaftspraxis Herne

๐Ÿ‡ฉ๐Ÿ‡ช

Herne, Germany

Medizinische Hochschule Hannover

๐Ÿ‡ฉ๐Ÿ‡ช

Hannover, Germany

Agaplesion Markus Krankenhaus

๐Ÿ‡ฉ๐Ÿ‡ช

Frankfurt am Main, Germany

Asklepios Westklinikum Hamburg

๐Ÿ‡ฉ๐Ÿ‡ช

Hamburg, Germany

Universitaetsklinik Koln

๐Ÿ‡ฉ๐Ÿ‡ช

Koln, Germany

Klinikum Luneburg

๐Ÿ‡ฉ๐Ÿ‡ช

Lรผneburg, Germany

Universitatsklinikum Jena

๐Ÿ‡ฉ๐Ÿ‡ช

Jena, Germany

Gastroenterologische Gemeinschaftspraxis Minden

๐Ÿ‡ฉ๐Ÿ‡ช

Minden, Germany

Universitaetsklinikum Tuebingen

๐Ÿ‡ฉ๐Ÿ‡ช

Tuebingen, Germany

Klinikum der Universitat Munchen - Grosshadern

๐Ÿ‡ฉ๐Ÿ‡ช

Muenchen, Germany

Universitatsklinikum Ulm, Zentrum Fur Innere Medizin

๐Ÿ‡ฉ๐Ÿ‡ช

Ulm, Germany

General Hospital of Athens "Hippokratio", 2nd Internal Medicine Clinic of Athens University, Hepato-gastroenterology Unit

๐Ÿ‡ฌ๐Ÿ‡ท

Athens, Greece

Princess Margaret Hospital

๐Ÿ‡ญ๐Ÿ‡ฐ

Hong Kong, Hong Kong

Bekes Megyei Kosponti Korhaz, Dr. Rethy Pal Tagkorhaz, IV. Belgyogyaszat - 2. Gasztroenterologia

๐Ÿ‡ญ๐Ÿ‡บ

Bekescsaba, Hungary

Szent Janos Korhaz es Eszak-budai Egitett Korhazak, I. Belgyogyaszati - Gasztroenterologiai Osztaly

๐Ÿ‡ญ๐Ÿ‡บ

Budapest, Hungary

Bugat Pal Korhaz, Belgyogyaszat

๐Ÿ‡ญ๐Ÿ‡บ

Gyรถngyรถs, Hungary

Karolina Korhaz es Rendelointezet, Altalanos Belgyogyaszat-Gasztroenterologia

๐Ÿ‡ญ๐Ÿ‡บ

Mosonmagyarovar, Hungary

Debreceni Egyetem Klinikai Kozpont, II. sz. Belgyogyaszati Klinika, Gasztroenterologia

๐Ÿ‡ญ๐Ÿ‡บ

Debrecen, Hungary

Citizens Specialty Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Hyderabad, India

S.M.S Medical College & Hospitals

๐Ÿ‡ฎ๐Ÿ‡ณ

Jaipur, India

Grant Medical Foundation Ruby Hall Clinic

๐Ÿ‡ฎ๐Ÿ‡ณ

Pune, India

Midas Multispeciality Hospital Pvt. Ltd

๐Ÿ‡ฎ๐Ÿ‡ณ

Nagpur, India

Suretech Hospital & Research Centre Ltd

๐Ÿ‡ฎ๐Ÿ‡ณ

Nagpur, India

Shree Giriraj Multispeciality Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Rajkot, India

Rambam Medical Health Care Campus

๐Ÿ‡ฎ๐Ÿ‡ฑ

Haifa, Israel

Sterling Hospital

๐Ÿ‡ฎ๐Ÿ‡ณ

Vadodara, India

UOC Gastroenterologia II

๐Ÿ‡ฎ๐Ÿ‡น

Castellana Grotte, Italy

Rabin Medical Center

๐Ÿ‡ฎ๐Ÿ‡ฑ

Petah Tikva, Israel

Hadassah Medical Center

๐Ÿ‡ฎ๐Ÿ‡ฑ

Jerusalem, Israel

U.O. Fisiopatologia Digestiva

๐Ÿ‡ฎ๐Ÿ‡น

Catanzaro, Italy

Ospedale Clinicizzato SS. Annunziata - Dipartimento di Medicina

๐Ÿ‡ฎ๐Ÿ‡น

Chieti, Italy

UOC Gastroenterologia ed Endoscopia Digestiva

๐Ÿ‡ฎ๐Ÿ‡น

Roma, Italy

Osaka University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Suita, Osaka, Japan

Nagasaki University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Nagasaki-shi, Nagasaki, Japan

Istituto Clinico Humanitas

๐Ÿ‡ฎ๐Ÿ‡น

Rozzano, Italy

Medical Hospital, Tokyo Medical and Dental University

๐Ÿ‡ฏ๐Ÿ‡ต

Bunkyo-ku, Japan

Fukuoka University Chikushi Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Chikushino-shi, Japan

Japanese Red Cross Fukuoka Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Fukuoka-shi, Japan

Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Chuo-ku, Japan

Hiroshima University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Hiroshima, Japan

Kitakyushu City Hospital Organization Kitakyushu Municipal Medical Center

๐Ÿ‡ฏ๐Ÿ‡ต

Kitakyushu-shi, Japan

Fukuoka University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Jonan-ku, Japan

Yamanashi Prefectural Central Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Kofu-shi, Japan

University Hospital, Kyoto Prefectural University of Medicine

๐Ÿ‡ฏ๐Ÿ‡ต

Kyoto-shi, Japan

Kurume University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Kurume-shi, Japan

Hidaka Coloproctology Clinic

๐Ÿ‡ฏ๐Ÿ‡ต

Kurume-shi, Japan

Aichi Medical University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Nagakute-shi, Japan

Kitasato University Kitasato Institute Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Minato-ku, Japan

Saiseikai Niigata Daini Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Nishi-ku, Japan

Iwate Medical University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Morioka-shi, Japan

Hyogo College of Medicine College Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Nishinomiya, Japan

Ishida IBD Clinic

๐Ÿ‡ฏ๐Ÿ‡ต

Oita-shi, Japan

Kyorin University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Mitaka-shi, Japan

Okayama University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Okayama-city, Japan

Kinshukai Infusion Clinic

๐Ÿ‡ฏ๐Ÿ‡ต

Osaka, Japan

Osaka City University Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Osaka, Japan

Tokito Clinic

๐Ÿ‡ฏ๐Ÿ‡ต

Saitama, Japan

Shiga University of Medical Science Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Otsu, Japan

Wakakusa-Daiichi Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Osaka, Japan

Toho University Sakura Medical Center

๐Ÿ‡ฏ๐Ÿ‡ต

Sakura, Japan

Sapporo Higashi Tokushukai Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Sapporo-shi, Japan

National Hospital Organization Sendai Medical Center

๐Ÿ‡ฏ๐Ÿ‡ต

Sendai, Japan

Tokyo Yamate Medical Center

๐Ÿ‡ฏ๐Ÿ‡ต

Shinjuku-ku, Japan

Kagawa Prefectural Central Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Takamatsu-shi, Japan

National Hospital Organization Takasaki General Medical Center

๐Ÿ‡ฏ๐Ÿ‡ต

Takasaki-shi, Japan

Osaka Medical College Hospital

๐Ÿ‡ฏ๐Ÿ‡ต

Takatsuki, Japan

GASTROMED Kopon, Zmudzinski i Wspolnicy Sp. j. Specjalistyczne Centrum Gastrologii i Endoskopii

๐Ÿ‡ต๐Ÿ‡ฑ

Torun, Poland

H-T.Centrum Medyczne Spolka z Ograniczona Odpowiedzialnoscia Sp.K.

๐Ÿ‡ต๐Ÿ‡ฑ

Tychy, Poland

Centrum Zdrowia MDM

๐Ÿ‡ต๐Ÿ‡ฑ

Warszawa, Poland

Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych i Administacji w Warszawie

๐Ÿ‡ต๐Ÿ‡ฑ

Warszawa, Poland

Municipal City Clinical Hospital of the Emergency Medical Care, 1 st Therapy Department. Danylo Halytsky Lviv National Medical

๐Ÿ‡บ๐Ÿ‡ฆ

Chernivtsi, Ukraine

Regional Municipal Institution "Chernivtsi Regional Clinical Hospital", Surgical Department

๐Ÿ‡บ๐Ÿ‡ฆ

Chernivtsi, Ukraine

Medical Center LLC "Health Clinic"

๐Ÿ‡บ๐Ÿ‡ฆ

Vinnytsia, Ukraine

UF Clinical Research Center

๐Ÿ‡บ๐Ÿ‡ธ

Gainesville, Florida, United States

Tampa General Hospital

๐Ÿ‡บ๐Ÿ‡ธ

Tampa, Florida, United States

University of Louisville, Clinical Trials Unit

๐Ÿ‡บ๐Ÿ‡ธ

Louisville, Kentucky, United States

Mayo Clinic

๐Ÿ‡บ๐Ÿ‡ธ

Rochester, Minnesota, United States

Kansas City Research Institute

๐Ÿ‡บ๐Ÿ‡ธ

Kansas City, Missouri, United States

Consultants for Clinical Research

๐Ÿ‡บ๐Ÿ‡ธ

Cincinnati, Ohio, United States

UC Health Physicians Clifton

๐Ÿ‡บ๐Ÿ‡ธ

Cincinnati, Ohio, United States

Quality Medical Research

๐Ÿ‡บ๐Ÿ‡ธ

Nashville, Tennessee, United States

Vanderbilt University Medical Center - IBD Clinic

๐Ÿ‡บ๐Ÿ‡ธ

Nashville, Tennessee, United States

Gastroenterology Research of San Antonio

๐Ÿ‡บ๐Ÿ‡ธ

San Antonio, Texas, United States

Clinical Associates in Research Therapeutics of America, LLC

๐Ÿ‡บ๐Ÿ‡ธ

San Antonio, Texas, United States

McGuire DVAMC

๐Ÿ‡บ๐Ÿ‡ธ

Richmond, Virginia, United States

Royal University Hospital

๐Ÿ‡จ๐Ÿ‡ฆ

Saskatoon, Saskatchewan, Canada

University Medical Center Utrecht

๐Ÿ‡ณ๐Ÿ‡ฑ

Utrecht, Netherlands

Queen Mary Hospital

๐Ÿ‡ญ๐Ÿ‡ฐ

Hong Kong, Hong Kong

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