Fluciclovine-PET/CT for Bone Metastases From Prostate Adenocarcinoma
Not Applicable
Completed
- Conditions
- Prostate Adenocarcinoma
- Registration Number
- NCT03496844
- Lead Sponsor
- University of Arizona
- Brief Summary
Determine diagnostic accuracy of Axumin-PET positive bone lesion by confirmatory bone biopsy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 15
Inclusion Criteria
- Male
- Be ≥ 18 years of age
- Diagnosed with prostate cancer
- Be willing and able to provide informed consent
- Be informed of the investigational nature of this study
Exclusion Criteria
- Having a history of severe claustrophobia
- Weight exceeding 400lbs
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method True Positive and False Positive Rates of F-18 Fluciclovine-PET/CT Findings Compared to Bone Biopsy 1 year True positive and false positive rates of positive findings in the skeleton on F-18 fluciclovine-PET/CT scan compared to gold standard pathology from bone biopsy
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms does fluciclovine-PET/CT utilize to detect bone metastases in prostate adenocarcinoma?
How does fluciclovine-PET/CT compare to conventional imaging modalities like bone scintigraphy for prostate cancer bone metastases detection?
Which biomarkers are associated with Axumin-PET positivity in hormonal sensitive and resistant prostate adenocarcinoma subtypes?
What are the potential adverse events and safety management strategies for fluciclovine-PET/CT in prostate cancer patients?
Are there any combination approaches or competitor drugs that enhance the detection of bone metastases in prostate adenocarcinoma?
Trial Locations
- Locations (1)
University of Arizona
🇺🇸Tucson, Arizona, United States
University of Arizona🇺🇸Tucson, Arizona, United States