A Comparative Study of Serum and Fecal Calprotectin Levels in Necrotizing Enterocolitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 59
- 试验地点
- 1
- 主要终点
- The predictive value of serum and fecal calprotectin levels in necrotising enterocolitis (NEC)
研究概览
简要总结
Necrotizing enterocolitis (NEC) is a serious condition that can affect premature babies, leading to complications like intestinal damage and infection. In our study, we measured specific markers (called calprotectin) in blood and stool to understand how severe NEC is and predict outcomes. We found that these markers were higher in babies with more severe NEC (stage 3), especially in those who needed surgery or sadly did not survive. This information can help doctors detect NEC earlier, understand its severity, and make better decisions for treating affected babies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 3 Days 至 30 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •before 32 weeks of gestation with a birth weight of ≤1500 grams
排除标准
- •Infants whose families did not provide consent and those with congenital anomalies were excluded.
结局指标
主要结局
The predictive value of serum and fecal calprotectin levels in necrotising enterocolitis (NEC)
时间窗: 2 years
The predictive value of serum and fecal calprotectin levels in assessing NEC severity (stage 2 and stage 3), intestinal perforation, the need for surgery, and mortality.
次要结局
未报告次要终点
研究者
Sara EROL
Assoc Prof, MD
Ankara Yildirim Beyazıt University