ISRCTN34690731
Completed
未知
Multi-modality imaging to determine the role of calcification and inflammation on restenosis rates following lower limb angioplasty: The CIRLA Study
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Peripheral Arterial Disease
- Sponsor
- British Heart Foundation
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
2019 results in https://pubmed.ncbi.nlm.nih.gov/31202739/ (added 08/04/2020)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Aged 50 years or over (women aged 55 years or over)
- •2\. Symptomatic peripheral arterial disease (intermittent claudication / critical limb ischaemia)
- •3\. Undergoing superficial femoral artery angioplasty (PTA) or femoro\-popliteal vein bypass graft (FPBG)
- •4\. Patients with TASC A and B lesions for the PTA group (there will be no restriction with regard to disease severity on the FPBG group as long as the anastomosis is to the popliteal artery)
- •5\. Taking standard antiplatelet/statin medication
Exclusion Criteria
- •1\. Inability to undergo PET/CT
- •2\. Presence of end stage renal failure
- •3\. Metastatic malignancy
- •4\. Patients undergoing adjunct endovascular procedures in the infrainguinal segments – PTA group only (e.g. Bare Metal Stent, Drug Eluting Balloon, Drug Eluting Stent)
- •5\. Previous ipsilateral femoral artery angioplasty within the previous 6 months – PTA group only
- •6\. Women under the age of 55 years
- •7\. Patients with diabetes mellitus taking insulin
Outcomes
Primary Outcomes
Not specified
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