MedPath

Effects of Lidocaine Spray for Reducing Pain During Endometrial Aspiration Biopsy : a Randomized Controlled Trial

Phase 3
Completed
Conditions
Uterine Bleeding
Interventions
Other: Normal saline spray
Registration Number
NCT03075358
Lead Sponsor
Chiang Mai University
Brief Summary

Endometrial aspiration biopsy has been accepted as a diagnostic procedure of choice for women with abnormal uterine bleeding to examine endometrial pathology. The procedure has high accuracy comparing to conventional fractional curettage. However, it is associated with significant pain during the procedure. In general, there is no specific recommendation regarding the proper anesthesia used during the procedure.

The aim of this study is to examine the effect of lidocaine spray for reducing pain during the endometrial aspiration procedure by comparing it with placebo and no intervention.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
240
Inclusion Criteria
  • Women undergoing endometrial aspiration biopsy at Maharaj Nakorn Chiang Mai hospital
Exclusion Criteria
  • Lidocaine allergy
  • Pregnancy
  • Previous uterine or cervical surgical procedures
  • Neurological abnormalities
  • Coagulopathy
  • Infection of cervix, vagina, or pelvic cavity
  • Taking any analgesic drugs within 4 hours before the procedure

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Normal saline sprayNormal saline spray-
Lidocaine sprayLidocaine spray-
Primary Outcome Measures
NameTimeMethod
Aspiration painImmediately following endometrial aspiration biopsy

A visual analog scale pain score associated with endometrial aspiration biopsy

Postprocedure pain10 minute after procedure completion

A visual analog scale pain score after the procedure

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of OB-GYN, Faculty of Medicine, Chiang Mai University

🇹🇭

Chiang Mai, Thailand

© Copyright 2025. All Rights Reserved by MedPath