Assessing Best Medical Treatment Patterns of Patients With Symptomatic Peripheral Arterial Occlusive Disease in Germany - A GermanVasc Study
试验速览
- 阶段
- 不适用
- 入组人数
- 60,000
- 主要终点
- Number of participants receiving best-medical-treatment
研究概览
简要总结
This proposed study will be conducted to support real-world-evidence on the extent of best medical treatment for secondary prevention of patients with symptomatic peripheral arterial occlusive disease (PAOD) for prevention of worsening limb symptoms or of major adverse cardiovascular events. The overall objective of this study is to gain a better understanding of patient characteristics, treatment patterns and outcomes in PAOD patients. For this purpose the investigators will analyze a patient population hospitalized either with intermittent claudication (IC) or chronic limb-threatening ischaemia (CLTI) while taking prior PAOD-related diagnoses in the outpatient setting into account. In detail, we study differentials according to age, calendar time, sex, disease severity and hospital procedure. Data were extracted from available German health insurance claims.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Incomplete information on sex, age, date of hospital discharge
- •Less than 5 years of insurance membership before index stay
结局指标
主要结局
Number of participants receiving best-medical-treatment
时间窗: at 12 months after discharge
Prevalence of the outpatient prescription of best medical treatment defined as picking up a medication at a pharmacy for a lipid-lowering, an antithrombotic, and an antihypertensive drug agent, within 12 months after index discharge for POAD according to information provided in health insurance claims data
次要结局
- Number of participants with a myocardial infarction(at 5 years after discharge)
- Number of participants with a major bleeding(at 5 years after discharge)
- Number of participants deceased(at 5 years after discharge)
- Lower extremity amputation(at 5 years after discharge)
- Number of participants with a stroke or transient ischaemic attack(at 5 years after discharge)
研究者
Christian Behrendt
Head of Research Unit GermanVasc and Principal Investigator
Universitätsklinikum Hamburg-Eppendorf