A comparison of respiratory effects of propofol and remimazolam during procedural sedation: a randomized controlled trial.
- Conditions
- Not Applicable
- Registration Number
- KCT0006797
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 70
1) Patients with the ASA PS class I~III
2) Patients scheduled for the insertion of central venous access port devices for the delivery of chemotherapy under monitored anesthetic care(MAC)
1) Patients with severe cognitive dysfunction
2) Body Mass Index > 35 kg / m 2 or <18.5 kg / m 2
3) Severe liver disease
4) Neuromuscular disease or mental illness kidney disease (GRF <30 or under hemodialysis)
5) Those diagnosed with metabolic diseases
6) Drug addiction or alcohol addiction
7) People who have contraindications to benzodiazepine, sevoflurane, or propofol
(Patients who have allergies to drugs or have a history of hypersensitivity reactions)
8) acute narrow-angle glaucoma
9) intolerance to galactose, deficiency of Lapp lactase, glucose-galactose absorption disorder
10) severe hypersensitivity to dextran 40
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Respiratory depression
- Secondary Outcome Measures
Name Time Method Interventions due to respiratory depression;time to sedation level of MOAAS 2-3 ;time to alertness from the end of the procedure;atelectasis at PACU ;Patient's satisfaction;The operator's satisfaction;Amnesia during the procedure;apnea hypoapnea index ;Tidal volume, minute ventilation, respiratory rate