Study of Whether There is Renal Retention of Lipid Microbubble Ultrasound Contrast Agents
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Renal Video Intensity Units
Study Overview
Brief Summary
Flank pain has been reported with ultrasound (US) contrast agents. The purpose of this study is to determine whether there is retention of ultrasound contrast agents in the renal microcirculation, which has been described in mice.
Detailed Description
In this study patients undergoing clinically indicated contrast echocardiography will have renal ultrasound performed 10 minutes after completion of contrast infusion to determine the presence and location of renal retention of lipid microbubbles.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Undergoing clinically indicated contrast echo
- •adequate renal ultrasound images
Exclusion Criteria
- •chronic inflammatory disease
- •known kidney disease
- •immunomodulatory therapy
Outcomes
Primary Outcomes
Renal Video Intensity Units
Time Frame: 10 min
Video intensity units in the kidney 10 min after completion of a clinically indicated contrast echocardiography study.
Secondary Outcomes
No secondary outcomes reported
Investigators
Jonathan R. Lindner, MD
Professor of Medicine
Oregon Health and Science University