Renal Retention of Microbubbles

Completed

• Conditions: - Study Focus: Renal Retention of Lipid Microbubbles

• Registration Number: NCT01647464
• Lead Sponsor: Oregon Health and Science University

Brief Summary

Flank pain has been reported with ultrasound (US) contrast agents. The purpose of this study is to determine whether there is retention of ultrasound contrast agents in the renal microcirculation, which has been described in mice.

Detailed Description

In this study patients undergoing clinically indicated contrast echocardiography will have renal ultrasound performed 10 minutes after completion of contrast infusion to determine the presence and location of renal retention of lipid microbubbles.

Study Timeline

• Study Start: 2012-07
• Study First Submitted: 2012-07-19
• Study First Submitted QC: 2012-07-20
• Study First Posted: 2012-07-23
• Primary Completion: 2012-10
• Study Completion: 2012-10
• Results First Submitted: 2015-10-23
• Status Verified: 2016-03
• Results First Submitted QC: 2016-03-28
• Last Update Submitted: 2016-03-28
• Results First Posted: 2016-04-28
• Last Update Posted: 2016-04-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Undergoing clinically indicated contrast echo
• adequate renal ultrasound images

Exclusion Criteria

• chronic inflammatory disease
• known kidney disease
• immunomodulatory therapy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Renal Video Intensity Units	10 min	Video intensity units in the kidney 10 min after completion of a clinically indicated contrast echocardiography study.

Trial Locations

Locations (1)

Oregon Health & Science University; 🇺🇸 Portland, Oregon, United States