Mentalization Based Treatment vs care as ususal in the treatment of severe Borderline Personality Disorder

Completed

Conditions: 'borderline'
Borderline Disorder
Borderline Personality Disorder
Personality disorder
10037173

Registration Number: NL-OMON33534

Lead Sponsor: Arkin (Amsterdam)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 72

Inclusion Criteria

A severe borderline personality disorder, based on standardized criteria for borderline personality disorder, assessed with the Dutch version of the Structured Clinical Interview for DSM-III-R (SCID-II) and the Borderline Personality Disorder Severity Index (BPDSI). Patients need to fullfill the criteria for borderline personality disorder as determined with the SCID-I, and need to have a total score on the BPDSI of > 25 indicating a severe borderline personality disorder.

Exclusion Criteria

•Schizophrenia, as determined with the SCID-I,
•Bipolar disorder, as determined with the SCID-I,
•Substance dependency or misuse, as primary disorder as determined with the SCID-I
•Organic brain disorder,
•Mental impairment (IQ < 80)
•Inadequate mastery of the Dutch language
•Legal incapacity

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome variable is the frequency and severity of manifestations of<br /><br>Borderline Personality Disorder as measured with the Borderline Personality<br /><br>Disorder Severity Index (BPDSI), a semi structured interview. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Suicide acts, self-mutilation: SSHI (Suïcide and Self-Harm Inventory),<br /><br>Depression: Beck Depression Inventory (BDI)<br /><br>Subjective experiences of symptoms: Symptom Checklist (SCL-90)<br /><br>Social and interpersonal functioning: Inventory of Interpersonal Problems (IIP)<br /><br>Personality functioning: Severity Indices of Personality Problems (SIPP)<br /><br>Quality of life: EQ5D<br /><br>Adherence to treatment: Realised Dose Instrument (RD).<br /><br>Attachement style (HSL)<br /><br><br /><br>Consumption of (mental) health care: Tic-P<br /><br>Work characteristics: Tic-P<br /><br>Work characteristics: Tic-P<br /><br>Additional costutility: QALY*s (Quality Adjusted Life Years<br /><br><br /><br><br /><br><br /><br><br /><br><br /><br>. </p><br>