Prevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admitted to Medical Intensive Care Units

Completed

• Conditions: Obesity Hypoventilation Syndrome

• Registration Number: NCT02934581
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

A prospective observation study to screen adult obese (BMI ≥30 kg/m2) patients who were newly admitted to the medical intensive care units and turned out to be diagnosed as Obesity hypoventilation syndrome(OHS). The investigators purpose is to look into the prevalence, predictive factors, and outcomes of OHS in these critically ill patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-10-29
• Primary Completion: 2016-08-12
• Study First Submitted: 2016-09-20
• Status Verified: 2016-10
• Study First Submitted QC: 2016-10-13
• Study First Posted: 2016-10-17
• Study Completion: 2018-10-31
• Last Update Submitted: 2021-03-10
• Last Update Posted: 2021-03-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• BMI ≥ 30 kg/m2
• Suspected chronic hypercapnia as following Paco2 ≥ 45 mmHg, HCO3- ≥ 27mEq/L or base excess, BE ≥ 2 mEq/L

Exclusion Criteria

• Malignancy with lung involvement
• Autoimmune disease with lung involvement
• Moderate to severe obstructive respiratory pattern via spirometry
• Uncontrolled endocrine disease
• Pregnancy
• Pneumonia confirmed by image
• Out-of-hospital cardiac arrest
• Lung edema
• Foreigner of Taiwan

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of obesity hypoventilation syndrome in Asian critically ill patients	2-year	Detecting obesity hypoventilation syndrome via screening obesity(BMI\>=30kg/m\^2) in critical care units in Asian.

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan