Effects of Low Fructose Diet on Glycemic Control in Patients With Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 48
- 主要终点
- Homeostatic model assessment and insulin resistance(HOMA-IR)
研究概览
简要总结
Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran. Suitable treatments for type 2 diabetes include changing lifestyle with exercise, nutrition, and drug use. New research suggests that added sugar, especially fructose, is the main trigger for diabetes and pre-diabetes even more potent than other carbohydrates. Fructose has a low glycemic index (23μg =) and slowly increases blood glucose levels. Therefore, it is thought that replacing fructose instead of glucose can have a positive effect on glycemic control of diabetic patients..
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of 70-40 years
- •body mass index(BMI) between 18.5 and 27
- •Type 2 diabetes People who only control their diabetes by using glucose lowering tablets Type 2 diabetes (1 to 10 years)
排除标准
- •Pregnancy and lactation
- •Thyroid gland disorders
- •Kidney disease and inflammation
- •Follow the weight loss regimen 6 months before starting the study
- •Usage of fatty and fatty foods, fiber powder Vitamin A Mineral Supplements, Omega 3
- •Taking glucocorticoid drugs and non-steroidal anti-inflammatory drugs
研究组 & 干预措施
intervention group
Eight weeks of low fructose diet with a maximum of 12 g of fructose
干预措施: low frutose diet (Other)
control group
Eight weeks of regular diabetic diet with a 15%pro 30%fat 55%CHO
结局指标
主要结局
Homeostatic model assessment and insulin resistance(HOMA-IR)
时间窗: 8weeks
insulin
时间窗: 8 weeks
fasting blood suger(FBS)
时间窗: 8 weeks
次要结局
- HDL-C(8 weeks)
- Triglyceride(8 weeks)
- Total cholestrole(8 weeks)
- Blood pressure(8 weeks)
- LDL-C(8 weeks)
研究者
Dr Azita Hekmatdoost
Principal Investigator
National Nutrition and Food Technology Institute