Evaluating the Impact of Androgen Deprivation Therapy on Cognition in an Australian Sample of Prostate Cancer Patients

Not Applicable

Suspended

• Conditions: Prostate Cancer; Cognitive function; Cancer - Prostate; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12616001007426
• Lead Sponsor: epean and Blue Mountains Local Health District

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-07-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Suspended
• Sex: Male
• Target Recruitment: 90

Inclusion Criteria

*Gender eligible for study: male
*Prostate cancer diagnosis
*MMSE > 24
*ECOG status between 0 – 1
*Speak and read English

ADT group
* Planned to commence ADT within 1 month

nADT group
* No prior or current ADT

Exclusion Criteria

Participants are not eligible to participate on the following basis:

*Commenced on ADT
*Prior ADT
*Previous or current chemotherapy treatment
*Previous or current severe psychiatric history as defined by
- A diagnosed mental illness involving psychosis
- Hospitalisation for mental health difficulties
*Current diagnosis of major depressive episode or an anxiety disorder
*Previous or current neurological difficulties e.g. Seizures or stroke
*Previous or current significant heart disease e.g. Myocardial infarction, Congestive Cardiac Failure
*History of brain cancer
*Patients with a past history of cancer in the 5 years before registration except for the following: Patients with squamous or basal cell carcinoma of the skin that has been effectively treated.
*Life expectancy less than 1 year
*Prior orchidectomy
*Participation in other projects involving cognitive testing.

Study & Design

• Study Type: Observational
• Study Design: Not specified