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临床试验/CTRI/2025/08/093367
CTRI/2025/08/093367尚未招募2/3 期

A CLINICAL STUDY TO EVALUATE THE EFFICACY OF DHATRI KHADIRADI KASHAYAM AND AVALGUJADI LEPA IN THE MANAGEMENT OF SHWITRA VITILIGO

Pandit Khushilal Sharma Goverment Ayurveda College And Institute Bhopal1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年8月20日最近更新:
适应症

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
It is expected that at the end of the study we should be able to evaluate the outcome of Dhatrikhadiradi Kashayam and Avalgujadi lep in the management of Shwitra within thirty days of the trial

研究概览

简要总结

Various skin problems affect approximately 20-30% of the world population and worldwide prevalence of Shwitra is observed as 1-2%. Th The highest incidence has been recorded in India, based on dermatologic outpatient’s record. India is considered to have the highest prevalence in the world, at about 8.8% has also been reported irrespective of races especially to dark skinned colour.Shwitra is associated with significant quality -of-life impairment in routine activities, employment and many psychological as well as social problems for patients.Sometimes people with this condition may face discrimination, misconceptions about their appearance. Some individuals may experience feelings of embarrassment, isolation, low self-esteem due to societal

attitudes towards their skin condition. Ayurveda has reached zenith of knowledge in samhita kala regarding the application of Lepa for therapeutic and cosmetic purpose. Therefore, there is a need for study to re-establish the concept of Lepana Karma and Aushadha Yoga already described in the Samhita. Drugs mentioned in Dhatrikhadiradi Kashayam are mainly Tridoshamak, Raktaprasadak in nature,soit can be used internally and katu tikta rasa, ruksha guna, katu vipak of the Bakuchi and ushna guna of Gomutra increase blood circulation locally or help in adequate formation of Prakrut Bhrajak Pitta in the skin. These two formulations that may be effectively treat Shwitra along with increasing the quality of life.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 55.00 Year(s)(—)
性别
All

入选标准

  • Patients age group between 18-55years Patients having Shwitra patch with normal sensation in touch Patients who are willing to participate in the study Duration of the disease being 1-2 years.

排除标准

  • Patients suffering from other systemic disorders like renal failure hepatic disorders cancer HIV and endocrine system related disorders with prolonged medication history Shwitra due to Agnidagdha or other injuries Vranaja shwitra White patches on lips and genital organs Congenital Shwitra and other depigmentory disorders Shwitra caused by other autoimmune conditions Pregnant and lactating women Exanthematous rashes or any other inflammatory skin disease.

结局指标

主要结局

It is expected that at the end of the study we should be able to evaluate the outcome of Dhatrikhadiradi Kashayam and Avalgujadi lep in the management of Shwitra within thirty days of the trial

时间窗: it is expected that within four weeks of the trial there will be significant result of the trial

次要结局

  • NA

研究者

发起方
Pandit Khushilal Sharma Goverment Ayurveda College And Institute Bhopal
申办方类型
Government funding agency
责任方
Principal Investigator
主要研究者

Pooja Badadwal

Pandit Khushilal Sharma Goverment Ayurveda College And Institute Bhopal

研究点 (1)

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