Are Exercise Capacity and Physical Fitness Related With Quality of Life, Physical Activity, Cognitive Health and Health Literacy in Dyslipidemia

Completed

• Conditions: Dyslipidemias
• Interventions: Diagnostic Test: Exercise Capacity Assessment; Diagnostic Test: Physical Fitness Assessment; Other: Quality of Life Assessment; Other: Physical Activity Assessment; Other: Cognitive Health Assessment; Other: Health Literacy Assessment

• Registration Number: NCT06563154
• Lead Sponsor: Çankırı Karatekin University

Brief Summary

There is insufficient literature explaining the relationship between exercise capacity and physical fitness of dyslipidemia patients and quality of life, cognitive status and health literacy. Our aim with this study is to provide more information to the scientific literature about the relationship between exercise capacity and physical fitness and quality of life and health literacy in dyslipidemia patients.

Detailed Description

Lipid profile disorders (especially high total blood cholesterol levels) are considered a significant public health problem worldwide and it is reported that approximately one in three people are exposed to risk factors that can lead to dyslipidemia. Prevalence studies conducted worldwide show that lipid profile disorders vary between 6.9% and 43.6%. Today, ischemic heart and central nervous system diseases are reported to be the most important causes of mortality and morbidity in the adult population globally. It is accepted that lipid profile disorders are the leading risk factors that cause ischemic heart diseases in particular. Since lipid profile disorders are caused by many different genetic and environmental factors, their incidence varies according to regions, lifestyle habits and individual factors. Apart from individual factors, lipid weight in the diet and lack of other nutrients that balance lipid metabolism, physical activity level and inactivity, other existing comorbid diseases and medical treatments change lipid metabolism in individuals and may lead to deterioration in lipid profile. In particular, lifestyle habits are the most easily modifiable factors that affect lipid metabolism. Studies conducted to evaluate the effect of genetic factors have shown that blood lipid levels are generally higher in Caucasians (especially total plasma cholesterol), that plasma high-density lipoprotein (HDL) levels are lower in East-Southeast Asian societies, and that plasma lipid density is generally lower in Hispanic societies. These studies have also indicated that these differences in lipid profiles are seen in the ethnic group examined in isolation when compared to other ethnic groups living in the same region, and therefore that dyslipidemia also has a genetic origin. It is recommended to follow multifaceted approaches when treating lipid profile disorders. Dietary counseling and exercise therapy are generally recommended to be included in these approaches. Exercise therapy is considered a very important treatment option, especially for controlling and treating obesity, hypertension, hyperglycemia, and metabolic syndrome symptoms that may accompany dyslipidemia. Physical activity is defined as body movements that create skeletal muscle contraction and increase energy expenditure. Exercise is a specialized type of physical activity that focuses on working specific muscle groups within a structured program for a specific purpose. Physical activity and exercise are beneficial for health and have a positive effect on psychological function, quality of life, morbidity, and cardiorespiratory fitness. Physical activity and exercise also increase self-esteem and social participation, while reducing depression and other related mental symptoms.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2023-06-15
• Primary Completion: 2023-06-15
• Study Completion: 2023-12-14
• Study First Submitted: 2024-08-17
• Study First Submitted QC: 2024-08-17
• Study First Posted: 2024-08-20
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-03
• Last Update Posted: 2024-12-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• Being followed up with a diagnosis of dyslipidemia,
• Being between the ages of 18-65,
• Being willing to participate in the study.

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Exclusion Criteria

• Having an orthopedic, neurological, cardiac, pulmonary or rheumatological disease that may affect functional capacity,
• Having a psychiatric disorder that may affect cooperation,
• Refusing to participate in the study.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patient Group	Quality of Life Assessment	-
Patient Group	Exercise Capacity Assessment	-
Patient Group	Physical Fitness Assessment	-
Patient Group	Health Literacy Assessment	-
Patient Group	Physical Activity Assessment	-
Patient Group	Cognitive Health Assessment	-

Primary Outcome Measures

Name	Time	Method
Physical Fitness	Second Day
Exercise Capacity	First Day

Secondary Outcome Measures

Name	Time	Method
Quality of Life Assessment	Second Day
Health Literacy	Second Day
Physical Activity	Second Day
Cognitive Health	Second Day

Trial Locations

Locations (1)

Hacettepe University; 🇹🇷 Ankara, Turkey