Cold snare polypectomy with submucosal injection versus cold snare polypectomy without submucosal injection for colorectal polyps 3-9 mm: a randomized controlled trial

Phase 3

• Conditions: Colorectal polyps; colonoscopy, polyp, cold snare polypectomy, submucosal injection

• Registration Number: TCTR20240805001
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-05
• Last Update Posted: 19 August 2024
• Study Completion: 2026-10-31

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 340

Inclusion Criteria

Patients aged 40-79 years, and undergoing screening or surveillance colonoscopy with at least one endoscopically diagnosed adenomatous or sessile serrated polyps measuring 3-9 mm.

Exclusion Criteria

The participants with endoscopically suspicious of malignant polyps, inflammatory bowel disease, familial polyposis syndrome, use of anticoagulant or antiplatelet therapy, known coagulopathy, pregnancy, or those who do not consent to participate in the study will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incomplete resection rate 1 month after the procedure Percent

Secondary Outcome Measures

Name	Time	Method
En bloc resection rate At the day of colonoscopy Percent,Procedural time At the day of colonoscopy Second,Specimen fragmentation rate At the day of colonoscopy Percent,Procedural adverse events until 1 month after procedure Percent,Resection depth assessed by the pathologists (included muscularis mucosae or submucosa or not) 1 month after procedure Percent