MUPPET; Motor Unit and muscle strength changes in PostPolio syndrome, Evaluation after Ten years.
- Conditions
- Postpoliomyelitis SyndromePPS10029317
- Registration Number
- NL-OMON34659
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
(1) All PPS subjects who participated in the trial by Horemans et al in 1999-2000*
(2) All controls who participated in the study described by Drost et al in the same period**;* Horemans HL, Nollet F, Beelen A et al. Pyridostigmine in postpolio syndrome: no decline in fatigue and limited functional improvement. J Neurol Neurosurg Psychiatry. 2003;74:1655-1661
**Drost G, Stegeman DF, Schillings ML et al. Motor unit characteristics in healthy subjects and those with postpoliomyelitis syndrome: a high-density surface EMG study. Muscle Nerve. 2004;30:269-276.
All participants of the trials of Horemans et al and Drost et al are eligible for participation unless they suffer from:
(1) Legal incompetence (incapacity), e.g. due to dementia
(2) Motor neuron disease or neurological disease that affects voluntary control of the quadriceps muscle under investigation.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method