Comparison Between Pericapsular Nerve Group Block (Peng) and Morphine Infusion in Reducing the Pain of Proximal Femur Fracture in the Emergency Department, a Randomized Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- morphine consumption
研究概览
简要总结
The pericapsular nerve group block (PENG) is a regional anaesthetic technique that was developed in 2018, primarily for total hip arthroplasties (THA) as a postoperative analgesia modality with motor sparing benefits.
The block is thought to provide more complete analgesia to the hip by depositing local anaesthetic within the myofascial plane of the psoas muscle and superior pubic ramus.
In this study, the investigators will assess the effect of pericapsular nerve group (PENG) block on pain control in patients with proximal femur fracture in the emergency department.
The Control group will receive morphine as regular patient control analgesia (PCA) The interventional group will receive PENG block before being attached to regular morphine PCA
详细描述
The pericapsular nerve group block (PENG) is a regional anaesthetic technique that was developed in 2018, primarily for total hip arthroplasties (THA) as a postoperative analgesia modality with motor sparing benefits.
The block is thought to provide more complete analgesia to the hip by depositing local anaesthetic within the myofascial plane of the psoas muscle and superior pubic ramus.
The indications for THA often include degenerative hip disease and traumatic hip fractures. These indications for surgery are relatively common in the elderly population and are associated with significant morbidity and mortality.
Operative intervention, such as THA, has also been associated with significant pain.
Historically, the most commonly performed peripheral nerve blocks include a lumbar plexus block, a femoral nerve block, or a fascia iliaca compartment block to manage post-operative analgesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients are aged 18-70 years.
- •Patients are ASA I (American Society of Anesthesiology physical status Grade I) = (normal healthy patients) or ASA II (American Society of Anesthesiologists physical status grade II) = (patients with mild systemic disease and no functional limitations).
- •Patients having post-traumatic pain associated with fractures of the proximal femur or femoral head.
排除标准
- •Patient refusal to participate in the study
- •Known allergy to LA.
- •Body mass index (BMI) more than 40 kg/m2
- •Heart block greater than first degree
- •Renal, and hepatic dysfunction
- •Underlying coagulopathies
研究组 & 干预措施
PENG block+ morhine
the participants will receive PENG block before being attached to morphine PCA
干预措施: Pericapsular nerve group block (Procedure)
PENG block+ morhine
the participants will receive PENG block before being attached to morphine PCA
干预措施: Morphine Sulfate (Drug)
MORPHINE
The participants will be given morphine PCA without PENG block
干预措施: Morphine Sulfate (Drug)
结局指标
主要结局
morphine consumption
时间窗: immediately at the end of 24 hours
compare the total morphine consumption in milligrams that is given by patient-controlled analgesia device (PCA)
次要结局
- Numeric rating scale (NRS)(immediately after starting morphine infusion 0,2,4,6,8,10,12,14,16,18,20,22,24 hours at rest)
- Incidence of nausea and vomiting(immediately after starting morphine infusion 0,2,4,6,8,10,12,14,16,18,20,22,24 hours at rest)
研究者
Abdelrhman Alshawadfy
Lecturer of anesthesia and intensive care
Suez Canal University