Clinical study to evaluate the combined effect of Dashamoola ksheera basti and Rakta Chandana Yoga oral administration in Vandhyatwa w.s.r.to female infertility.

Phase 2/3

Not yet recruiting

• Conditions: Unspecified symptoms and signs involving the genitourinary system. Ayurveda Condition: VANDHYA,

• Registration Number: CTRI/2023/11/059719
• Lead Sponsor: Shri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital Udupi

Brief Summary

In classics, Vandhyatwa is seen as a condition which occurs as a complication of untreated Yonivyapat, Artavavyapat and Asrigdhara. Vandhyatwa is one among the 80 Vataja Nanatmaja Vikaras.Vata is mandatorily involved in the pathology of all the Yonivyapat and

Artavavyapat.

Basti, being Ardha Chikitsa which is said to be Paramaushadha for treatmentbof Vata disorders,tackles all the gynecological pathologies of Vata including Vandhyatwa.

Sahacharadi Taila is selected for Anuvasna Basti. As Sahachara is a potent Vatahara drug and Taila does Yoni Vishodhana. Dashamoola is best Vata kaphahara. Ksheera is Amritopama.

When Dashamoola is processed with ksheera, it acts best on Tridosha.Dashamoola Ksheera Niruha Basti is thus preferred.

Raktachandana is Vrishya and Apamarga is

Vatahara.

So, in this clinical trial oral administration of Raktachandana with ApamargaSwarasa has been taken, which is successfully practiced by the folklore practicionors.

So, aiming at finding out the best method of treatment for Infertility, this study istaken up to evaluate the combined effect of Dashamoola Ksheera Niruha Basti and

Rakthachandana Yoga oral administration in female Infertility



Patient will be evaluated before (0th day), at the end of the second course of Basti and oral

medication and on the day of follow up, based on subjective and objective parameters.

SUBJECTIVE PARAMETERS:

Attainment of Suddha Artava Lakshanas

OBJECTIVE PARAMETERS:

Conception evidenced by UPT and USG.

• Conceived

• not conceived

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-12
• Last Update Posted: 2023-08-11

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Patient who is in active marital life with partner having normal seminogram.
• Patients who are fit for basti.
• Patients with PCOD.
• Patients with Unexplained Infertility.
• Patients with Endometriosis and Adenomyosis.
• Patients with Chocolate cyst/Ovarian cyst measuring less than 4 cms.
• Patients presenting with Dysfunctional Uterine Bleedin.

Exclusion Criteria

• Patients with Genital infections.
• Patients with Bad obstetric history (Previous unfavorable fetal outcome in terms of 2 or more consecutive spontaneous abortions, early neonatal deaths, etc.) 3.
• Patients with premature ovarian failure.
• Patients with Congenital anomalies of uterus.
• Patients with surgical factors including uterine fibroids, cervical polyp, pin hole cervical os etc.
• Patients with hydrosalpinx and tubal block.
• Patients with Sexually Transmitted Diseases such as HIV and HBsAg. 9.
• Any other systemic illness such as DM, HTN, Thyroid dysfunctio.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Conception evidenced by UPT and USG.	90 days

Secondary Outcome Measures

Name	Time	Method
Attainment of Shuddha Artava Lakshana	1 month (will be assessed on next/following menstrual cycle)

Trial Locations

Locations (1)

Shri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital Udupi; 🇮🇳 Udupi, KARNATAKA, India

Shri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital Udupi

🇮🇳Udupi, KARNATAKA, India

Dr P Deepika bhat

Principal investigator

8660819737

pdeepikabhat@gmail.com