Preventing abdominal surgical wound infections with negative pressure wound therapy dressings

Phase 3

Completed

• Conditions: Superficial surgical site infection; Infections and Infestations

• Registration Number: ISRCTN43457163
• Lead Sponsor: Westmead Hospital

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33516795/ (added 15/11/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-22
• Study Completion: 2020-10-31
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 127

Inclusion Criteria

1. Age 16 years or over
2. Any gender
3. Undergoing elective or emergency laparotomy
4. All general surgical sub-disciplines were potentially included in the study
5. Patients undergoing minimally invasive surgery converted to laparotomy were also included

Exclusion Criteria

1. Hypersensitivity to silver
2. Patients without capacity to consent, pregnancy
3. Patients with pre-existing laparostomy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> The incidence of superficial SSI diagnosed on the basis of the following CDC criteria:<br> 1. Purulent drainage, with or without laboratory confirmation, from within the wound<br> 2. Organisms isolated from an aseptically obtained culture of fluid from the incision<br> 3. At least one of the following signs or symptoms of infection: pain or tenderness, localized swelling, redness and superficial incision deliberately opened by the surgeon, unless incision is culture-negative<br> 4. Diagnosis of superficial incisional SSI by the independent assessor<br> Assessed by the treating doctors on postoperative day 5-7 and then on day 30<br>